Risk Factors for Surgical Site Infection After Cardiac Surgery in Neonates: A Case-Control Study

Overview

Journal J Clin Med

Specialty General Medicine

Date 2025 Jan 8

PMID 39768678

Authors

Vitaliy V Suvorov

Dmitri O Ivanov

Affiliations

Soon will be listed here.

Abstract

This study was undertaken to determine the incidence and risk factors associated with the development of sternal wound infection in neonates after surgery for congenital heart disease. A case-control study was conducted to examine the influence of perioperative risk factors on the development of sternal infection. In total, 253 neonates with CHD underwent a complete median sternotomy. To identify the risk factors influencing the development of sternal infection, multivariable logistic regression analysis was used. Overall, 15 (5.9%) patients developed sternal wound infection after surgery. Deep wound infection occurred in six (2.4%) cases. As a result, the perioperative risk factors were the level of oxygen delivery in the postoperative period (OR: 0.956; CI: 0.933-0.98; < 0.001), duration of intubation after surgery (OR: 1.04; CI: 1.003-1.079; = 0.034) and application of surgical manipulation features (OR: 0.0004; CI: 0.000007-0.027; < 0.001). The incidence of sternal infection in newborns can be reduced by simple and affordable methods. This will decrease the cost of patient care, length of hospitalization and the risk of secondary complications.

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