Changes in Retinal Nerve Fiber Layer and Vessel Densities After Scleral Buckling in Patients with Rhegmatogenous Retinal Detachment Observed by OCTA

Overview

Journal Front Med (Lausanne)

Specialty General Medicine

Date 2024 Dec 30

PMID 39735706

Authors

Cuiwen Zhang

Linlin Liu

Yiping Jiang

Affiliations

Soon will be listed here.

Abstract

Purpose: To observe the changes in peripapillary retinal nerve fiber layer (RNFL) thickness and peripapillary vessel densities (VD) in patients with rhegmatogenous retinal detachment (RRD) after scleral buckling (SB) by OCTA.

Methods: A total of 40 patients (40 eyes) with monocular RRD who underwent SB were included in the study, with the operated eyes (40 eyes) as the study group and the contralateral healthy eyes (40 eyes) as the control to analyse the changes in peripapillary RNFL thickness and VD before and after surgery. Data were analysed by paired samples -test or Wilcoxon signed rank sum test.

Results: Comparison of the peripapillary RNFL thickness in the 8 areas between the two groups during the 6-month follow-up period: All 8 peripapillary areas of the optic disc were statistically different before surgery, except for the tempo superior and tempo inferior, which were statistically different at each postoperative follow-up point, and the remaining 6 areas in the operated eyes group were progressively closer to those in the healthy eyes group, and there was no significant difference between the two groups. Comparison of peripapillary VD in the 8 areas between the two groups during the 6-month follow-up: Peripapillary VD in the 8 areas in the two groups were all statistically different before surgery, and except for superior tempo, which was statistically different at each postoperative follow-up time point, the remaining seven areas in the operated eyes group became progressively closer to that in the healthy eyes group and there was no significant difference.

Conclusion: RRD negatively affects the peripapillary RNFL, but both peripapillary RNFL thickness and VD gradually improved in the operated eyes close to the contralateral eyes after SB.

References

. The classification of retinal detachment with proliferative vitreoretinopathy. Ophthalmology. 1983; 90(2):121-5. DOI: 10.1016/s0161-6420(83)34588-7. View

Pichi F, Hay S, Abboud E . Inner retinal toxicity due to silicone oil: a case series and review of the literature. Int Ophthalmol. 2020; 40(9):2413-2422. DOI: 10.1007/s10792-020-01418-0. View

Feltgen N, Walter P . Rhegmatogenous retinal detachment--an ophthalmologic emergency. Dtsch Arztebl Int. 2014; 111(1-2):12-21. PMC: 3948016. DOI: 10.3238/arztebl.2014.0012. View

Kunikata H, Abe T, Nakazawa T . Historical, Current and Future Approaches to Surgery for Rhegmatogenous Retinal Detachment. Tohoku J Exp Med. 2019; 248(3):159-168. DOI: 10.1620/tjem.248.159. View

Fang D, Yang D, Mai X, Cheung C, Chen H . Repeatability, interocular correlation and agreement of optic nerve head vessel density in healthy eyes: a swept-source optical coherence tomographic angiography study. Int J Ophthalmol. 2024; 17(5):896-903. PMC: 11074198. DOI: 10.18240/ijo.2024.05.14. View

Lu B, Zhang P, Liu H, Jia H, Yu Y, Wang F . Peripapillary Vessel Density in Eyes with Rhegmatogenous Retinal Detachment after Pars Plana Vitrectomy. J Ophthalmol. 2021; 2021:6621820. PMC: 8009721. DOI: 10.1155/2021/6621820. View

Mason R, Minaker S, Marafon S, Figueiredo N, Hillier R, Muni R . Retinal displacement following rhegmatogenous retinal detachment: A systematic review and meta-analysis. Surv Ophthalmol. 2022; 67(4):950-964. DOI: 10.1016/j.survophthal.2022.01.002. View

Moledina M, Charteris D, Chandra A . The Genetic Architecture of Non-Syndromic Rhegmatogenous Retinal Detachment. Genes (Basel). 2022; 13(9). PMC: 9498391. DOI: 10.3390/genes13091675. View

Yoshida A, Hirokawa H, Ishiko S, Ogasawara H . Ocular circulatory changes following scleral buckling procedures. Br J Ophthalmol. 1992; 76(9):529-31. PMC: 504341. DOI: 10.1136/bjo.76.9.529. View

10.

Cetinkaya Yaprak A, Kucuk M, Yaprak L, Erol M . Change in retinal and choroidal microvascular structures after rhegmatogenous retinal detachment surgery and effects on visual recovery. J Fr Ophtalmol. 2021; 44(6):804-812. DOI: 10.1016/j.jfo.2020.11.027. View

11.

Fallico M, Longo A, Avitabile T, Alosi P, Grillo M, Castellino N . Microvascular Changes after Scleral Buckling for Rhegmatogenous Retinal Detachment: An Optical Coherence Tomography Angiography Study. Diagnostics (Basel). 2022; 12(12). PMC: 9776469. DOI: 10.3390/diagnostics12123015. View

12.

Inan S, Polat O, Ozcan S, Inan U . Comparison of Long-Term Automated Retinal Layer Segmentation Analysis of the Macula between Silicone Oil and Gas Tamponade after Vitrectomy for Rhegmatogenous Retinal Detachment. Ophthalmic Res. 2020; 63(6):524-532. DOI: 10.1159/000506382. View

13.

Jiang J, Li R, Zhou J, Li R, Wang R, Wang X . Peripapillary changes after vitrectomy and silicone oil tamponade for rhegmatogenous retinal detachment. Indian J Ophthalmol. 2021; 69(12):3579-3583. PMC: 8837374. DOI: 10.4103/ijo.IJO_508_21. View

14.

Lee Y, Lee J, Shin Y, Lee K, Jo Y, Kim J . Longitudinal changes in retinal nerve fiber layer thickness after vitrectomy for rhegmatogenous retinal detachment. Invest Ophthalmol Vis Sci. 2012; 53(9):5471-4. DOI: 10.1167/iovs.12-9782. View

15.

Gao Y, Ruan T, Chen N, Yu B, Xing X, Du Q . A Comparison of Face-Down Positioning and Adjustable Positioning After Pars Plana Vitrectomy for Macular Hole Retinal Detachment in High Myopia. Front Med (Lausanne). 2022; 9:780475. PMC: 8889034. DOI: 10.3389/fmed.2022.780475. View

16.

Ozdek S, Lonneville Y, Onol M, Gurelik G, Hasanreisoglu B . Assessment of retinal nerve fiber layer thickness with NFA-GDx following successful scleral buckling surgery. Eur J Ophthalmol. 2003; 13(8):697-701. DOI: 10.1177/112067210301300806. View

17.

Nagahara M, Tamaki Y, Araie M, Eguchi S . Effects of scleral buckling and encircling procedures on human optic nerve head and retinochoroidal circulation. Br J Ophthalmol. 1999; 84(1):31-6. PMC: 1723226. DOI: 10.1136/bjo.84.1.31. View

18.

Vu A, Alber S, Chang M, Park S . Prospective Cross-Sectional Study of Repeatability of Peripapillary Capillary Density Measurement Using Optical Coherence Tomography Angiography in Eyes With Optic Nerve and Retinal Vascular Pathology. J Neuroophthalmol. 2021; 42(1):73-78. PMC: 8514563. DOI: 10.1097/WNO.0000000000001216. View

19.

Raczynska D, Mitrosz K, Raczynska K, Glasner L . The Influence of Silicone Oil on the Ganglion Cell Complex After Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment. Curr Pharm Des. 2018; 24(29):3476-3493. DOI: 10.2174/1381612824666180813115438. View

20.

Zabel P, Zabel K, Kazmierczak K, Stankiewicz M, Jaworski D, Suwala K . Vascular density and macular sensitivity in eyes after scleral buckling surgery for macula-on rhegmatogenous retinal detachment. PLoS One. 2023; 18(3):e0279683. PMC: 9980809. DOI: 10.1371/journal.pone.0279683. View