Application of Autophagy in Mesenchymal Stem Cells

Overview

Journal World J Stem Cells

Publisher Baishideng Publishing Group

Date 2024 Dec 30

PMID 39734481

Authors

Min Chai

Chun-Yan Zhang

Shuai Chen

Da-Hai Xu

Affiliations

Soon will be listed here.

Abstract

In this editorial, we have taken an in-depth look at the article published by Wan . The study showed that preconditioning mesenchymal stem cells (MSCs) protected them against programmed cell death, and increased their survival rate and therapeutic potential. Autophagy, a type of programmed cell death, is a major intracellular degradation and recycling pathway that is crucial for maintaining cellular homeostasis, self-renewal, and pluripotency. We have explored the relationship between autophagy and MSCs to determine the role of autophagy in the therapeutic applications of MSCs.

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