Phenotypic and Genotypic Characterization of Clinical Carbapenem-resistant Species Harboring the Metallo-beta-lactamases IMP-8 or NDM-1 in China

Overview

Journal Microbiol Spectr

Specialty Microbiology

Date 2024 Dec 27

PMID 39727411

Authors

Qingye Xu

Xinli Mu

Jintao He

Haiyang Liu

Xiaochen Liu

Yanfei Wang

Xiaoting Hua

Yunsong Yu

Affiliations

Soon will be listed here.

Abstract

Importance: Given the low prevalence of IMP among and the limited sequencing technology in earlier years, research on in is scarce, and genetic information on -producing spp. strains isolated in earlier years is limited. This study revisited five MBL-carrying spp. strains isolated in 2010, characterizing their phenotypic and genotypic features. This retrospective analysis serves as a form of "bacterial archaeology," providing evidence of the evolutionary changes in genetic elements conferring antibiotic resistance.

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