Updated Meta-analysis for Antihypertensive Treatment Guided by Home Blood Pressure Compared to Treatment Based on Office Blood Pressure: Systematic Review

Overview

Journal Hypertens Res

Specialty Cardiology & Vascular Diseases

Date 2024 Dec 24

PMID 39719531

Authors

Tatsuya Maruhashi

Yukako Tatsumi

Michihiro Satoh

Yusuke Kobayashi

Yukako Ogoyama

Atsushi Sakima

Hisatomi Arima

Takayoshi Ohkubo

Affiliations

Soon will be listed here.

Abstract

Home blood pressure (BP) measurement is widely used, and home BP plays a central role in hypertension management in clinical practice in Japan. We updated the systematic review to determine whether home BP-based antihypertensive treatment is superior to office BP-based treatment in improving clinical outcomes, including BP levels, in adult patients with essential hypertension. A literature search identified 14 randomized controlled trials (RCTs). The results of meta-analysis revealed that home BP-based antihypertensive treatment was significantly associated with greater reductions in ambulatory systolic BP by 2.73 mmHg (95% confidence interval [CI], -5.23 to -2.22 mmHg; p = 0.03) and ambulatory diastolic BP by 1.61 mmHg (95% CI, -3.21 to -0.01 mmHg; p = 0.05) compared to office BP-based treatment. No RCTs evaluating cardiovascular outcomes other than ambulatory BP reduction were identified. Consistent with the previous review, this updated meta-analysis revealed home BP-based antihypertensive treatment is strongly recommended over office BP-based treatment for BP control in patients with essential hypertension.

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