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Short-Term Intermittent Normobaric Hypoxia Combined with Light Exercise Improves Acclimatization of Cardiorespiratory Function in Inactive Adults

Overview
Publisher Dove Medical Press
Specialty Orthopedics
Date 2024 Dec 24
PMID 39717075
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Abstract

Background: Un-acclimatized individuals may experience acute altitude illness. Thus, the current study investigated the impact of short-term intermittent normobaric hypoxia (NH) combined with light exercise on the acclimatization of cardiorespiratory function to altitude in inactive adults.

Methods: This quasi-experimental study recruited 10 inactive university students (age: 26.3 ± 2.53 years). All participants were instructed to perform light exercise while exposed to intermittent NH (15%) (2 h/d) for 2 weeks continuously. The heart rate (HR), relative oxygen consumption (VO2 mL/kg/min), minute ventilation (VE), VO2/HR, and respiratory frequency (RF) were measured.

Results: Results illustrated a significant improvement in participants' cardiorespiratory functions by 10 days after exposure to NH, as compared to day 1 of exposure, based on their HR, RF, and VE responses at rest and HR, RF, VE, VO2, VO2/kg, and VO2/HR during light exercise. Resting-state values had returned to the pre-NH exposure levels after 10 days of intermittent NH exposure. Furthermore, values measured during light exercise were significantly decreased on days 10 and 14 as compared to day 1 of NH exposure.

Conclusion: This study concluded that as few as 10 days of exposure to intermittent NH (pO2 = 15%) combined with light exercise may improve the acclimation to NH of 15% pO2 in inactive adults.

References
1.
Ambrozy T, Maciejczyk M, Klimek A, Wiecha S, Stanula A, Snopkowski P . The Effects of Intermittent Hypoxic Training on Anaerobic and Aerobic Power in Boxers. Int J Environ Res Public Health. 2020; 17(24). PMC: 7765038. DOI: 10.3390/ijerph17249361. View

2.
Rosales A, Shute R, Hailes W, Collins C, Ruby B, Slivka D . Independent effects of acute normobaric hypoxia and hypobaric hypoxia on human physiology. Sci Rep. 2022; 12(1):19570. PMC: 9666440. DOI: 10.1038/s41598-022-23698-5. View

3.
Abut F, Akay M, George J . Developing new VOmax prediction models from maximal, submaximal and questionnaire variables using support vector machines combined with feature selection. Comput Biol Med. 2016; 79:182-192. DOI: 10.1016/j.compbiomed.2016.10.018. View

4.
West J . High-altitude medicine. Am J Respir Crit Care Med. 2012; 186(12):1229-37. DOI: 10.1164/rccm.201207-1323CI. View

5.
Khalaf T, Ramadan M, Al-Ashaikh R . How many days are required for workers to acclimatize to heat?. Work. 2017; 56(2):285-289. DOI: 10.3233/WOR-162485. View