Use Multiple Mechanisms to Disseminate from the Intestinal Lamina Propria to the Mesenteric Lymph Nodes

Overview

Journal Microbiol Spectr

Specialty Microbiology

Date 2024 Dec 23

PMID 39714174

Authors

Joshua S Nowacki

Grant S Jones

Sarah E F DOrazio

Affiliations

Soon will be listed here.

Abstract

Importance: Consumption of the foodborne bacterial pathogen results in a wide spectrum of human disease from mild self-limiting gastroenteritis to life-threatening infections of the bloodstream, brain, and placenta. It is not well understood how the bacteria migrate from the intestines to the draining mesenteric lymph nodes, which are thought to serve as the last barrier to prevent systemic infections. Results presented here reveal multiple redundant mechanisms can use to disseminate from the ileum or colon to the mesenteric lymph nodes.

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