What's New in the Pediatric Spine?

Overview

Journal J Child Orthop

Publisher Sage Publications

Specialty Pediatrics

Date 2024 Dec 23

PMID 39713179

Authors

Brice Ilharreborde

Ilkka Helenius

Daniel Studer

Carol Hasler

Moyo Kruyt

Jorge Mineiro

Dror Ovadia

David Farrington

Sebastien Pesenti

Muharrem Yazici

Affiliations

Soon will be listed here.

Abstract

Introduction: The field of pediatric spine surgery has encountered major changes and evolutions lately, with new treatment options available and the development of enabling technologies. This article aims to summarize the most relevant recent literature.

Materials And Methods: The five most relevant topics were selected and assigned to one or two authors who performed a comprehensive Pubmed database search for articles published in the last 4 years (2021-2024). Only studies with a high level of evidence or clinical relevance were reported.

Results: Thirty-nine articles were selected and analyzed, covering the following subjects: treatment options in tweeners, the impact of new medical treatments in pediatric spine practice, the emergence of new surgical techniques, the development of enabling technologies in scoliosis surgery, and recent relevant randomized controlled trials.

Discussion: Many new surgical concepts and techniques have been developed lately, but their results need to be further assessed on specific subgroups of patients. Numerous significant medical improvements have been reported in the last 5 years, affecting positively the management of syndromic and neuromuscular patients.

References

Baroncini A, Courvoisier A . The different applications of Vertebral Body Tethering - Narrative review and clinical experience. J Orthop. 2023; 37:86-92. PMC: 10039119. DOI: 10.1016/j.jor.2023.02.012. View

Ip H, Yu M, Wong W, Liu A, Kwan K, Chan S . Treatment of Symptomatic Spinal Muscular Atrophy with Nusinersen: A Prospective Longitudinal Study on Scoliosis Progression. J Neuromuscul Dis. 2024; 11(2):349-359. PMC: 10977416. DOI: 10.3233/JND-230077. View

Wijdicks S, Lemans J, Verkerke G, Noordmans H, Castelein R, Kruyt M . The potential of spring distraction to dynamically correct complex spinal deformities in the growing child. Eur Spine J. 2020; 30(3):714-723. DOI: 10.1007/s00586-020-06612-3. View

Solla F, Ilharreborde B, Clement J, Rose E, Monticone M, Bertoncelli C . Patient-Specific Surgical Correction of Adolescent Idiopathic Scoliosis: A Systematic Review. Children (Basel). 2024; 11(1). PMC: 10814112. DOI: 10.3390/children11010106. View

Kothari A, Katkade S, Bhilare P, Aiyer S, Situt N, Hadgaonkar S . "Critical pedicle wall" breaches analysis in complex spinal deformity using O-arm navigation. Surg Neurol Int. 2023; 14:306. PMC: 10559569. DOI: 10.25259/SNI_437_2023. View

Coratti G, Lenkowicz J, Pera M, DAmico A, Bruno C, Gulli C . Early treatment of type II SMA slows rate of progression of scoliosis. J Neurol Neurosurg Psychiatry. 2023; 95(3):235-240. DOI: 10.1136/jnnp-2023-332084. View

Miladi L, Khouri N, Pradon J, Elie C, Treluyer J . One-way self-expanding rod for early-onset scoliosis: early results of a clinical trial of 20 patients. Eur Spine J. 2021; 30(3):749-758. DOI: 10.1007/s00586-021-06732-4. View

Herdea A, Dragomirescu M, Ulici A, Lungu C, Charkaoui A . Controlling the Progression of Curvature in Children and Adolescent Idiopathic Scoliosis Following the Administration of Melatonin, Calcium, and Vitamin D. Children (Basel). 2022; 9(5). PMC: 9140159. DOI: 10.3390/children9050758. View

Soini V, Schreiber G, Wilken B, Hell A . Early Development of Spinal Deformities in Children Severely Affected with Spinal Muscular Atrophy after Gene Therapy with Onasemnogene Abeparvovec-Preliminary Results. Children (Basel). 2023; 10(6). PMC: 10297104. DOI: 10.3390/children10060998. View

10.

Siu J, Wu H, Saggi S, Allahabadi S, Katyal T, Diab M . Radiographic and perioperative outcomes following anterior thoracic vertebral body tethering and posterior lumbar spine tethering: a pilot series. Spine Deform. 2023; 11(6):1399-1408. PMC: 10587020. DOI: 10.1007/s43390-023-00717-7. View

11.

Trobisch P, Castelein R, Da Paz S . Radiographic outcome after vertebral body tethering of the lumbar spine. Eur Spine J. 2023; 32(6):1895-1900. DOI: 10.1007/s00586-023-07740-2. View

12.

Chiu C, Wang W, Lee Y, Chung W, Wei Chan C, Kwan M . What is the prevalence and distribution of narrow dysplastic and fully corticalized pedicles in Asian adolescent idiopathic scoliosis patients with major main thoracic curves? A computed tomography scan analysis of 6,494 pedicles. Spine J. 2023; 23(11):1700-1708. DOI: 10.1016/j.spinee.2023.07.006. View

13.

Akazawa T, Torii Y, Ueno J, Umehara T, Iinuma M, Yoshida A . Accuracy of computer-assisted pedicle screw placement for adolescent idiopathic scoliosis: a comparison between robotics and navigation. Eur Spine J. 2022; 32(2):651-658. DOI: 10.1007/s00586-022-07502-6. View

14.

Sussman M, Sienko S, Buckon C, Hilton C, De Mattos C, dAmato C . Efficacy of corticosteroid in decreasing scoliosis and extending time to loss of ambulation in a single clinic: an effectiveness trial. J Child Orthop. 2020; 14(5):421-432. PMC: 7666798. DOI: 10.1302/1863-2548.14.200156. View

15.

Hammad A, Emar M, Shahin F, Aljuba A, Hasani A, Awad M . A Prospective Multicenter ≥2 Years Clinical Study of the Active Apex Correction (APC) Technique in Early Onset Scoliosis (EOS) Patients. Global Spine J. 2024; 15(2):1174-1185. PMC: 11571920. DOI: 10.1177/21925682241229677. View

16.

Ansorge A, Sarwahi V, Bazin L, Vazquez O, De Marco G, Dayer R . Accuracy and Safety of Pedicle Screw Placement for Treating Adolescent Idiopathic Scoliosis: A Narrative Review Comparing Available Techniques. Diagnostics (Basel). 2023; 13(14). PMC: 10378125. DOI: 10.3390/diagnostics13142402. View

17.

Llopis-Ibor C, Mariscal G, de la Rubia Orti J, Barrios C . Incidence of vitamin D deficiency in adolescent idiopathic scoliosis: a meta-analysis. Front Endocrinol (Lausanne). 2023; 14:1250118. PMC: 10598863. DOI: 10.3389/fendo.2023.1250118. View

18.

Virkki E, Holstila M, Kolari T, Lastikka M, Mattila K, Malmi S . Elastic Lumbar Support Versus Rigid Thoracolumbar Orthosis for Acute Pediatric Spondylolysis: A Prospective Controlled Study. Spine (Phila Pa 1976). 2022; 48(2):89-96. DOI: 10.1097/BRS.0000000000004424. View

19.

Ferizovic N, Summers J, de Zarate I, Werner C, Jiang J, Landfeldt E . Prognostic indicators of disease progression in Duchenne muscular dystrophy: A literature review and evidence synthesis. PLoS One. 2022; 17(3):e0265879. PMC: 8956179. DOI: 10.1371/journal.pone.0265879. View

20.

Matsumoto H, Fano A, Quan T, Akbarnia B, Blakemore L, Flynn J . Re-evaluating consensus and uncertainty among treatment options for early onset scoliosis: a 10-year update. Spine Deform. 2022; 11(1):11-25. DOI: 10.1007/s43390-022-00561-1. View