» Articles » PMID: 39713022

A Blood-based Metabolite Signature for Personalized Risk Assessment of Pancreatic Cancer

Overview
Date 2024 Dec 23
PMID 39713022
Authors
Affiliations
Soon will be listed here.
References
1.
Zhang T, Gao G, Sakandar H, Kwok L, Sun Z . Gut Dysbiosis in Pancreatic Diseases: A Causative Factor and a Novel Therapeutic Target. Front Nutr. 2022; 9:814269. PMC: 8885515. DOI: 10.3389/fnut.2022.814269. View

2.
Shirasu H, Todaka A, Omae K, Fujii H, Mizuno N, Ozaka M . Impact of UGT1A1 genetic polymorphism on toxicity in unresectable pancreatic cancer patients undergoing FOLFIRINOX. Cancer Sci. 2018; 110(2):707-716. PMC: 6361560. DOI: 10.1111/cas.13883. View

3.
Mirji G, Worth A, Bhat S, El Sayed M, Kannan T, Goldman A . The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer. Sci Immunol. 2022; 7(75):eabn0704. PMC: 9925043. DOI: 10.1126/sciimmunol.abn0704. View

4.
Querio G, Antoniotti S, Geddo F, Levi R, Gallo M . Modulation of Endothelial Function by TMAO, a Gut Microbiota-Derived Metabolite. Int J Mol Sci. 2023; 24(6). PMC: 10054148. DOI: 10.3390/ijms24065806. View

5.
Ye D, Guan K, Xiong Y . Metabolism, Activity, and Targeting of D- and L-2-Hydroxyglutarates. Trends Cancer. 2018; 4(2):151-165. PMC: 5884165. DOI: 10.1016/j.trecan.2017.12.005. View