The Genetic Architecture of Resistance to Septoria Tritici Blotch in French Wheat Cultivars

Overview

Journal BMC Plant Biol

Publisher Biomed Central

Specialty Biology

Date 2024 Dec 20

PMID 39701973

Authors

Jean-Noel Thauvin

Sandrine Gelisse

Florence Cambon

Thierry Langin

Thierry C Marcel

Cyrille Saintenac

Affiliations

Soon will be listed here.

Abstract

Background: Septoria tritici blotch (STB) is one of the most damaging wheat diseases worldwide, and the development of resistant cultivars is of paramount importance for sustainable crop management. However, the genetic basis of the resistance present in elite wheat cultivars remains largely unknown, which limits the implementation of this strategy. A collection of 285 wheat cultivars originating mostly from France was challenged with ten Zymoseptoria tritici isolates at the seedling stage. The collection was further evaluated in seven field trials across France using artificial inoculation.

Results: Genome-wide association study resulted in the detection of 57 wheat QTL, among which 40 were detected at the seedling stage. Three quarters of these QTL were in genomic regions previously reported for to confer resistance to Z. tritici, but 10 QTL are novel and may be of special interest as new sources of resistance. Some QTL colocalise with major Stb resistance genes, suggesting their presence in the French elite winter wheat germplasm. Among them, the three QTL with the strongest effect colocalize with Stb6, Stb9 and Stb18. There was minimal overlap between the QTL detected at the seedling and adult plant stages, with only 1 out of 20 seedling QTL also being detected in field trials inoculated with the same isolate. This suggests that different resistance genes are involved at the seedling and adult plant stages.

Conclusion: This work reveals the highly complex genetic architecture of French wheat resistance to STB and provides relatively small QTL intervals, which will be valuable for identifying the underlying causative genes and for marker-assisted selection.

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