Imaging in Esophageal Cancer: A Comprehensive Review

Overview

Journal Indian J Radiol Imaging

Publisher Thieme

Specialty Radiology

Date 2024 Dec 19

PMID 39697520

Authors

Pallavi Talasila

Swaroop G Hedge

Kannan Periasamy

Satish Subbiah Nagaraj

Harmandeep Singh

Harjeet Singh

Pankaj Gupta

Affiliations

Soon will be listed here.

Abstract

Esophageal cancer is one of the common cancers. Risk factors are well recognized and lead most commonly to two distinct histological subtypes (squamous cell carcinoma and adenocarcinoma). The diagnosis is based on endoscopic evaluation. The most challenging aspect of management is accurate staging as it guides appropriate management. Endoscopic ultrasound, computed tomography (CT), positron emission tomography-CT, and magnetic resonance imaging are the imaging tests employed for the staging. Each imaging test has its own merits and demerits. Imaging is also critical to evaluate posttreatment complication and for response assessment. In this review article, we discuss in detail the risk factors, anatomical aspects, and role of imaging test in staging and evaluation of complications and response after treatment.

References

Zhang J, Hu W, Zang L, Yao Y, Tang Y, Qian Z . Clinical investigation on application of water swallowing to MR esophagography. Eur J Radiol. 2011; 81(9):1980-5. DOI: 10.1016/j.ejrad.2011.05.010. View

Quint L, Bogot N . Staging esophageal cancer. Cancer Imaging. 2008; 8 Spec No A:S33-42. PMC: 2582495. DOI: 10.1102/1470-7330.2008.9007. View

Daiko H, Kato K . Updates in the 8th edition of the TNM staging system for esophagus and esophagogastric junction cancer. Jpn J Clin Oncol. 2020; 50(8):847-851. DOI: 10.1093/jjco/hyaa082. View

Iyer R, Silverman P, Tamm E, Dunnington J, DuBrow R . Diagnosis, staging, and follow-up of esophageal cancer. AJR Am J Roentgenol. 2003; 181(3):785-93. DOI: 10.2214/ajr.181.3.1810785. View

Yamada I, Murata Y, Izumi Y, Kawano T, Endo M, Kuroiwa T . Staging of esophageal carcinoma in vitro with 4.7-T MR imaging. Radiology. 1997; 204(2):521-6. DOI: 10.1148/radiology.204.2.9240547. View

Riddell A, Allum W, Thompson J, Wotherspoon A, Richardson C, Brown G . The appearances of oesophageal carcinoma demonstrated on high-resolution, T2-weighted MRI, with histopathological correlation. Eur Radiol. 2006; 17(2):391-9. DOI: 10.1007/s00330-006-0363-6. View

Mariette C, Markar S, Dabakuyo-Yonli T, Meunier B, Pezet D, Collet D . Hybrid Minimally Invasive Esophagectomy for Esophageal Cancer. N Engl J Med. 2019; 380(2):152-162. DOI: 10.1056/NEJMoa1805101. View

Yamada I, Hikishima K, Miyasaka N, Tokairin Y, Kawano T, Ito E . Diffusion-tensor MRI and tractography of the esophageal wall ex vivo. J Magn Reson Imaging. 2014; 40(3):567-76. DOI: 10.1002/jmri.24411. View

Tang Y, Zhang X, Yang Z, Huang Y, Chen T, Chen Y . The Blood Oxygenation T Values of Resectable Esophageal Squamous Cell Carcinomas as Measured by 3T Magnetic Resonance Imaging: Association with Tumor Stage. Korean J Radiol. 2017; 18(4):674-681. PMC: 5447643. DOI: 10.3348/kjr.2017.18.4.674. View

10.

Wei Y, Wu S, Gao F, Sun T, Zheng D, Ning P . Esophageal carcinoma: Ex vivo evaluation by high-spatial-resolution T -mapping MRI compared with histopathological findings at 3.0T. J Magn Reson Imaging. 2016; 45(6):1609-1616. DOI: 10.1002/jmri.25509. View

11.

Picus D, Balfe D, Koehler R, ROPER C, OWEN J . Computed tomography in the staging of esophageal carcinoma. Radiology. 1983; 146(2):433-8. DOI: 10.1148/radiology.146.2.6849089. View

12.

Weissleder R, Elizondo G, Wittenberg J, Lee A, Josephson L, Brady T . Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging. Radiology. 1990; 175(2):494-8. DOI: 10.1148/radiology.175.2.2326475. View

13.

Puli S, Reddy J, Bechtold M, Antillon D, Ibdah J, Antillon M . Staging accuracy of esophageal cancer by endoscopic ultrasound: a meta-analysis and systematic review. World J Gastroenterol. 2008; 14(10):1479-90. PMC: 2693739. DOI: 10.3748/wjg.14.1479. View

14.

Mannell A . Carcinoma of the esophagus. Curr Probl Surg. 1982; 19(10):553-647. DOI: 10.1016/0011-3840(82)90006-5. View

15.

Ajani J, DAmico T, Bentrem D, Cooke D, Corvera C, Das P . Esophageal and Esophagogastric Junction Cancers, Version 2.2023, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2023; 21(4):393-422. DOI: 10.6004/jnccn.2023.0019. View

16.

Nishimura H, Tanigawa N, Hiramatsu M, Tatsumi Y, Matsuki M, Narabayashi I . Preoperative esophageal cancer staging: magnetic resonance imaging of lymph node with ferumoxtran-10, an ultrasmall superparamagnetic iron oxide. J Am Coll Surg. 2006; 202(4):604-11. DOI: 10.1016/j.jamcollsurg.2005.12.004. View

17.

Yamada I, Hikishima K, Miyasaka N, Kawano T, Tokairin Y, Ito E . Esophageal carcinoma: ex vivo evaluation with diffusion-tensor MR imaging and tractography at 7 T. Radiology. 2014; 272(1):164-73. DOI: 10.1148/radiol.14132170. View

18.

Akiyama Y, Iwaya T, Endo F, Nikai H, Sato K, Baba S . Thoracoscopic esophagectomy with total meso-esophageal excision reduces regional lymph node recurrence. Langenbecks Arch Surg. 2018; 403(8):967-975. DOI: 10.1007/s00423-018-1727-5. View

19.

Lee S, Yadav P, Starekova J, Christensen L, Chandereng T, Chappell R . Diagnostic Performance of MRI for Esophageal Carcinoma: A Systematic Review and Meta-Analysis. Radiology. 2021; 299(3):583-594. DOI: 10.1148/radiol.2021202857. View

20.

Riddell A, Davies D, Allum W, Wotherspoon A, Richardson C, Brown G . High-resolution MRI in evaluation of the surgical anatomy of the esophagus and posterior mediastinum. AJR Am J Roentgenol. 2006; 188(1):W37-43. DOI: 10.2214/AJR.05.1795. View