Management of Febrile Neutropenia: Consensus of the Brazilian Association of Hematology, Blood Transfusion and Cell Therapy - ABHH

Overview

Journal Hematol Transfus Cell Ther

Specialty Hematology

Date 2024 Dec 18

PMID 39694764

Authors

Marcio Nucci

Celso Arrais-Rodrigues

Maria Daniela Bergamasco

Marcia Garnica

Ana Beatriz Firmato Gloria

Mariana Guarana

Clarisse Machado

Jessica Ramos

Marco Aurelio Salvino

Belinda Simoes

Affiliations

Soon will be listed here.

Abstract

Febrile neutropenia is a major complication of the treatment of patients with hematologic diseases. Recent epidemiologic changes, with an increase in infection caused by drug-resistant bacteria, represent a major challenge for the proper management of febrile neutropenia. The impact of these changes in the epidemiology of infection may vary according to the region. In this document we present recommendations from the Infectious Diseases Committee of the Brazilian Association of Hematology, Blood Transfusion and Cell Therapy (ABHH) for the management of febrile neutropenia in hematologic patients. The consensus was developed by ten experts in the field, using the Delphi methodology. In the document we provide recommendations for the initial workup, prophylaxis, empiric antibiotic and antifungal therapy, modifications in the empiric regimen and criteria for discontinuing antimicrobial therapy.

Citing Articles

Management of Febrile Neutropenia in a Tropical Country.

Rego E Hematol Transfus Cell Ther. 2024; 46 Suppl 6:S1-S2.

PMID: 39709227 PMC: 11726107. DOI: 10.1016/j.htct.2024.11.118.

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