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Early Intervention in Post-operative Infectious Spondylodiscitis: Outcome of Aggressive Transforaminal Lumbar Interbody Fusion

Overview
Journal Malays Orthop J
Specialty Orthopedics
Date 2024 Dec 18
PMID 39691573
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Abstract

Introduction: Conservative and surgical approach timeline in post-operative spondylodiscitis (POS) following lumbar disc herniation (LDH) surgery is ill defined, and patients have a protracted recovery phase with social, psychological, and financial implications.

Material And Methods: Retrospective analysis of patients operated by transforaminal lumbar interbody fusion (TLIF) in POS was done. Confirmed clinico-radiological diagnosed POS cases, not responding within three to four weeks were included. Normalisation of CRP and radiological stable reconstruction was assessed for objective clearance of POS and bony union.

Results: Ninety-five patients were included in the study with minimum follow-up period of two years. The mean age was 51.63±13.63 years. There were organisms cultured in 55 patients (57.89%). The ODI improvement of the patients was noted to improve from 88.71±5.3 to 20.80±9.7 (8 weeks) and was incremental at 2 years follow-up (10.12±6.41) and maintained further at final follow-up at 9±4.3. Bony union achieved in all with stable reconstruction. The resumption of activities of daily living (ADL) was quick (15.90±8.20 days) and job (3.67±1.31 months) was achieved in all the patients. In poor outcomes, two patients didn't respond, and one patient died due to uncontrolled infection.

Conclusion: Early diagnosis and intervention is the key to effective management of POS. Utilisation of aggressive TLIF yields faster ADL resumption.

References
1.
Wang B, Chen C, Hua W, Ke W, Lu S, Zhang Y . Minimally Invasive Surgery Oblique Lumbar Interbody Debridement and Fusion for the Treatment of Lumbar Spondylodiscitis. Orthop Surg. 2020; 12(4):1120-1130. PMC: 7454224. DOI: 10.1111/os.12711. View

2.
Liao J, Chen W . Revision Surgery for Postoperative Spondylodiscitis at Cage Level after Posterior Instrumented Fusion in the Lumbar Spine-Anterior Approach Is Not Absolutely Indicated. J Clin Med. 2020; 9(12). PMC: 7760829. DOI: 10.3390/jcm9123833. View

3.
Chen S, Chen W, Wu M, Liao J, Fu C . Postoperative Infection in Patients Undergoing Posterior Lumbosacral Spinal Surgery: A Pictorial Guide for Diagnosis and Early Treatment. Clin Spine Surg. 2018; 31(6):225-238. DOI: 10.1097/BSD.0000000000000633. View

4.
Santhanam R, Lakshmi K . A Retrospective Analysis of the Management of Postoperative Discitis: A Single Institutional Experience. Asian Spine J. 2015; 9(4):559-64. PMC: 4522446. DOI: 10.4184/asj.2015.9.4.559. View

5.
Toyone T, Tanaka T, Kato D, Kaneyama R, Otsuka M . Patients' expectations and satisfaction in lumbar spine surgery. Spine (Phila Pa 1976). 2005; 30(23):2689-94. DOI: 10.1097/01.brs.0000187876.14304.15. View