A Low Molecular Weight Extract of Bovine Serum Albumin Stimulates Rabbit Blastocyst Cell Division and Expansion in Vitro

Overview

Journal J Reprod Fertil

Specialty Reproductive Medicine

Date 1985 Jan 1

PMID 3968651

Citations 7

Authors

M T Kane

Affiliations

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Abstract

Fraction V bovine serum albumin (BSA) was dissolved in 5% formic acid and filtered through a molecular filter with a cutoff of Mr 10 000. The freeze-dried filtrate stimulated increased cell division of cultured rabbit morulae to blastocysts (up to 8-fold increase in cell number) and increased blastocyst expansion (greater than 2-fold). These results show that some samples of commercial BSA contain an embryonic growth factor of a low molecular weight.

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