Sleep Homeostatic and Circadian Clock Changes Can Be Obtained by Manipulating One Single Kinase, but Do the Two Processes Meet Each Other There?

Overview

Journal Sleep

Publisher Oxford University Press

Specialty Psychiatry

Date 2024 Dec 14

PMID 39673772

Authors

Tom Deboer

Affiliations

Soon will be listed here.

References

Franken P, Dijk D . Sleep and circadian rhythmicity as entangled processes serving homeostasis. Nat Rev Neurosci. 2023; 25(1):43-59. DOI: 10.1038/s41583-023-00764-z. View

Krone L, Yamagata T, Blanco-Duque C, Guillaumin M, Kahn M, van der Vinne V . A role for the cortex in sleep-wake regulation. Nat Neurosci. 2021; 24(9):1210-1215. PMC: 7612118. DOI: 10.1038/s41593-021-00894-6. View

Honda T, Fujiyama T, Miyoshi C, Ikkyu A, Hotta-Hirashima N, Kanno S . A single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice. Proc Natl Acad Sci U S A. 2018; 115(41):10458-10463. PMC: 6187192. DOI: 10.1073/pnas.1810823115. View

Deboer T . Behavioral and electrophysiological correlates of sleep and sleep homeostasis. Curr Top Behav Neurosci. 2013; 25:1-24. DOI: 10.1007/7854_2013_248. View

Kim S, Hotta-Hirashima N, Asano F, Kitazono T, Iwasaki K, Nakata S . Kinase signalling in excitatory neurons regulates sleep quantity and depth. Nature. 2022; 612(7940):512-518. DOI: 10.1038/s41586-022-05450-1. View

Daan S, Beersma D, Borbely A . Timing of human sleep: recovery process gated by a circadian pacemaker. Am J Physiol. 1984; 246(2 Pt 2):R161-83. DOI: 10.1152/ajpregu.1984.246.2.R161. View

Asano F, Kim S, Fujiyama T, Miyoshi C, Hotta-Hirashima N, Asama N . SIK3-HDAC4 in the suprachiasmatic nucleus regulates the timing of arousal at the dark onset and circadian period in mice. Proc Natl Acad Sci U S A. 2023; 120(11):e2218209120. PMC: 10089210. DOI: 10.1073/pnas.2218209120. View

Deboer T . Sleep homeostasis and the circadian clock: Do the circadian pacemaker and the sleep homeostat influence each other's functioning?. Neurobiol Sleep Circadian Rhythms. 2019; 5:68-77. PMC: 6584681. DOI: 10.1016/j.nbscr.2018.02.003. View

Saper C, Scammell T, Lu J . Hypothalamic regulation of sleep and circadian rhythms. Nature. 2005; 437(7063):1257-63. DOI: 10.1038/nature04284. View

10.

Borbely A . A two process model of sleep regulation. Hum Neurobiol. 1982; 1(3):195-204. View

11.

Borbely A, Daan S, Wirz-Justice A, Deboer T . The two-process model of sleep regulation: a reappraisal. J Sleep Res. 2016; 25(2):131-43. DOI: 10.1111/jsr.12371. View

12.

Funato H, Miyoshi C, Fujiyama T, Kanda T, Sato M, Wang Z . Forward-genetics analysis of sleep in randomly mutagenized mice. Nature. 2016; 539(7629):378-383. PMC: 6076225. DOI: 10.1038/nature20142. View

13.

Reichert C, Deboer T, Landolt H . Adenosine, caffeine, and sleep-wake regulation: state of the science and perspectives. J Sleep Res. 2022; 31(4):e13597. PMC: 9541543. DOI: 10.1111/jsr.13597. View

14.

Nakata S, Fujiyama T, Asano F, Komiya H, Hotta-Hirashima N, Juichi M . Partial activation of salt-inducible kinase 3 delays the onset of wakefulness and alleviates hypersomnia due to the lack of protein kinase A-phosphorylation site. Sleep. 2024; 48(2). PMC: 11807893. DOI: 10.1093/sleep/zsae279. View