» Articles » PMID: 39654663

Indian Perspective on Childhood Malnutrition: Prevalence, Pathophysiology, Risk Factors, and Prevention

Overview
Date 2024 Dec 10
PMID 39654663
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Childhood malnutrition contributes over half of the childhood mortality around the world, predominantly in South-Asian and sub-Saharan countries.

Aim: To summarize the childhood malnutrition epidemiology along with the comorbid factors associated with it and its management within the community.

Methods: The data collection process involved conducting a comprehensive search using specific keywords such as child nutrition disorders and India with Boolean operators. The search was conducted in the Scopus and PubMed electronic databases.

Results: Inadequate energy consumption initiates pathological alterations in the form of growth retardation, fat, visceral, and muscle loss, a reduction in basal metabolic rate, and a significant reduction in total energy expenditure. It has become evident that malnutrition shows an increased prevalence and incidence rate, despite available guidelines for the management of malnutrition.

Conclusion: Malnutrition can be a major player in the establishment of severe infections that result in significant post discharge mortalities in children. Future trials are required to fill the prime gaps in knowledge regarding the identification of other contributory factors in the pathogenesis of malnutrition and post-discharge infection. New biomarkers for early detection of malnutrition should be the priority of the scientific community for the early management of malnutrition.

References
1.
Schaible U, Kaufmann S . Malnutrition and infection: complex mechanisms and global impacts. PLoS Med. 2007; 4(5):e115. PMC: 1858706. DOI: 10.1371/journal.pmed.0040115. View

2.
Grellety E, Golden M . Severely malnourished children with a low weight-for-height have a higher mortality than those with a low mid-upper-arm-circumference: I. Empirical data demonstrates Simpson's paradox. Nutr J. 2018; 17(1):79. PMC: 6138885. DOI: 10.1186/s12937-018-0384-4. View

3.
Patel M, Sandige H, Ndekha M, Briend A, Ashorn P, Manary M . Supplemental feeding with ready-to-use therapeutic food in Malawian children at risk of malnutrition. J Health Popul Nutr. 2006; 23(4):351-7. View

4.
Bassaganya-Riera J, Berry E, Blaak E, Burlingame B, le Coutre J, van Eden W . Goals in Nutrition Science 2020-2025. Front Nutr. 2021; 7:606378. PMC: 7923694. DOI: 10.3389/fnut.2020.606378. View

5.
Das J, Salam R, Saeed M, Kazmi F, Bhutta Z . Effectiveness of Interventions for Managing Acute Malnutrition in Children under Five Years of Age in Low-Income and Middle-Income Countries: A Systematic Review and Meta-Analysis. Nutrients. 2020; 12(1). PMC: 7019612. DOI: 10.3390/nu12010116. View