Research Progress on the Pathogenesis of Multiple Symmetrical Lipomatosis

Overview

Journal Adipocyte

Specialties Cell Biology
Endocrinology
Physiology

Date 2024 Dec 9

PMID 39648639

Authors

Bo Hu

Ze Wang

Tengxiao Ma

Pengfei Fan

Lei Li

Affiliations

Soon will be listed here.

Abstract

Multiple symmetric lipomatosis, also known as madelung's disease, is a rare syndrome characterized by the accumulation of multiple symmetric subcutaneous adipose tissues that significantly affect patients' quality of life. Since the aetiology of the disease is still unclear, surgical intervention by doctors based on clinical experience is currently the main treatment. However, the recurrence rate remains high even after surgical intervention. Therefore, studying the pathogenesis of this disease is particularly important for overcoming this challenge. In this paper, we reviewed and summarized recent research results on the pathogenesis of this disease to provide possible research directions and treatment strategies for this disease, but no clear mechanism was identified.'Level of Evidence: Level I, Review Articles'.

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