» Articles » PMID: 39640338

A Rare Case of Cerebellar Abscess Caused by

Overview
Journal Surg Neurol Int
Specialty Neurology
Date 2024 Dec 6
PMID 39640338
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Gram-positive opportunistic bacteria of the species are responsible for a large spectrum of infections, such as pneumonia, skin infections, and more widespread conditions, including brain abscesses.

Case Description: A 67-year-old male patient suffered from headache, gait disorder, and vertigo for a week before admission to our department. An enhanced magnetic resonance imaging scan revealed a mediosagittal hyperintense infratentorial lesion with concomitant compression of the fourth ventricle. The patient underwent surgical treatment with general anesthesia. The frozen section did not reveal any tumoral tissue but rather a purulent content. He was comatose on the 1 postoperative day, and he underwent a follow-up computed tomography (CT) scan, which revealed triventricular hydrocephalus. The external ventricular drain was performed, and a follow-up CT scan revealed significant improvement of hydrocephalus. Matrix-Assisted Laser Desorption Ionization Time of Flight did not reveal any causative agent from the intraoperative content, but the 16s ribosomal DNA method confirmed . The patient was intravenously treated with ceftriaxone and trimethoprim/sulfamethoxazole and died on the 5 postoperative day.

Conclusion: Nocardiosis presents a rare Gram-positive bacterial infection that typically affects immunocompromised hosts. -caused brain abscesses present a significant challenge in its treatment for its atypical presentation and slow culture growth.

References
1.
Martinez-Barricarte R . Isolated Nocardiosis, an Unrecognized Primary Immunodeficiency?. Front Immunol. 2020; 11:590239. PMC: 7606290. DOI: 10.3389/fimmu.2020.590239. View

2.
Khorshidi M, Navid S, Azadi D, Shokri D, Shojaei H . A case report of brain abscess caused by in a diabetic patient. JMM Case Rep. 2018; 5(9):e005133. PMC: 6230754. DOI: 10.1099/jmmcr.0.005133. View

3.
Kennedy K, Chung K, Bowden F, Mews P, Pik J, Fuller J . A cluster of nocardial brain abscesses. Surg Neurol. 2007; 68(1):43-9. DOI: 10.1016/j.surneu.2006.08.067. View

4.
Saubolle M, Sussland D . Nocardiosis: review of clinical and laboratory experience. J Clin Microbiol. 2003; 41(10):4497-501. PMC: 254378. DOI: 10.1128/JCM.41.10.4497-4501.2003. View

5.
Stuebe C, Dayawansa S, Huang J, Harris F . Nocardia Brain Abscess Mimicking Metastases in an Immunocompromised Patient. Cureus. 2022; 13(12):e20248. PMC: 8730793. DOI: 10.7759/cureus.20248. View