» Articles » PMID: 39634558

Predictive Value of Machine Learning Model Based on CT Values for Urinary Tract Infection Stones

Overview
Journal iScience
Publisher Cell Press
Date 2024 Dec 5
PMID 39634558
Authors
Affiliations
Soon will be listed here.
Abstract

Preoperative diagnosis of infection stones presents a significant clinical challenge. We developed a machine learning model to predict urinary infection stones using computed tomography (CT) values, enabling preoperative identification. In this study, we included 1209 patients who underwent urinary lithotripsy at our hospital. Seven machine learning algorithms along with eleven preoperative variables were used to construct the prediction model. Subsequently, model performance was evaluated by calculating AUC and AUPR for subjects in the validation set. On the validation set, all seven machine learning models demonstrated strong discrimination (AUC: 0.687-0.947). Additionally, the XGBoost model was identified as the optimal model significantly outperforming the traditional LR model. Taken together, the XGBoost model is the first machine learning model for preoperative prediction of infection stones based on CT values. It can rapidly and accurately identify infection stones , providing valuable guidance for urologists in managing these stones.

References
1.
Marchini G, Gebreselassie S, Liu X, Pynadath C, Snyder G, Monga M . Absolute Hounsfield unit measurement on noncontrast computed tomography cannot accurately predict struvite stone composition. J Endourol. 2012; 27(2):162-7. DOI: 10.1089/end.2012.0470. View

2.
Bichler K, Eipper E, Naber K, Braun V, Zimmermann R, Lahme S . Urinary infection stones. Int J Antimicrob Agents. 2002; 19(6):488-98. DOI: 10.1016/s0924-8579(02)00088-2. View

3.
Harmon W, Sershon P, Blute M, Patterson D, Segura J . Ureteroscopy: current practice and long-term complications. J Urol. 1997; 157(1):28-32. DOI: 10.1016/s0022-5347(01)65272-8. View

4.
Talati V, Soares R, Khambati A, Nadler R, Perry Jr K . Trends in urinary calculi composition from 2005 to 2015: a single tertiary center study. Urolithiasis. 2019; 48(4):305-311. DOI: 10.1007/s00240-019-01151-z. View

5.
Gonzalez R, Whiting B, Canales B . The history of kidney stone dissolution therapy: 50 years of optimism and frustration with renacidin. J Endourol. 2011; 26(2):110-8. PMC: 3311908. DOI: 10.1089/end.2011.0380. View