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Two-dimensional Transition Metal Carbides and Nitrides (MXenes) Based Biosensing and Molecular Imaging

Overview
Journal Nanophotonics
Publisher De Gruyter
Date 2024 Dec 5
PMID 39634292
Authors
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Abstract

As a "star material", 2D transition metal carbides and/or nitrides (MXenes) have tremendous potential applications in biosensor development and molecular imaging. MXenes have a lot of advantages due to their large specific surface, excellent electrical conductivity, adjustable band gap, and easy modification. MXenes that immobilized with DNA strands, proteins, enzymes, or other bioluminescent materials on the surface, have been used to measure small molecules with extraordinary sensitivity and remarkable limit of detection. This review provides an overview of most recent development in the synthesis, fundamental properties, biosensing, and molecular imaging applications of MXenes. We focused on molecular detection through MXene-based electrochemical properties their challenges and novel opportunities of MXenes in biological applications. This article will provide a guide for researchers who are interested in the application of MXenes biosensors.

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References
1.
Urbankowski P, Anasori B, Makaryan T, Er D, Kota S, Walsh P . Synthesis of two-dimensional titanium nitride Ti4N3 (MXene). Nanoscale. 2016; 8(22):11385-91. DOI: 10.1039/c6nr02253g. View

2.
Chen W, Pan W, Wang J, Cheng L, Wang J, Song L . Emerging two-dimensional monoelemental materials (Xenes): Fabrication, modification, and applications thereof in the field of bioimaging as nanocarriers. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2021; 14(2):e1750. DOI: 10.1002/wnan.1750. View

3.
Song Y, Yan X, Ostermeyer G, Li S, Qu L, Du D . Direct Cytosolic MicroRNA Detection Using Single-Layer Perfluorinated Tungsten Diselenide Nanoplatform. Anal Chem. 2018; 90(17):10369-10376. DOI: 10.1021/acs.analchem.8b02193. View

4.
Yan B, Cheng Z, Lai C, Qiao B, Yuan R, Zhang C . Boosting the Photocatalytic Ability of TiO Nanosheet Arrays for MicroRNA-155 Photoelectrochemical Biosensing by Titanium Carbide MXene Quantum Dots. Nanomaterials (Basel). 2022; 12(20). PMC: 9611374. DOI: 10.3390/nano12203557. View

5.
Naguib M, Kurtoglu M, Presser V, Lu J, Niu J, Heon M . Two-dimensional nanocrystals produced by exfoliation of Ti3 AlC2. Adv Mater. 2011; 23(37):4248-53. DOI: 10.1002/adma.201102306. View