» Articles » PMID: 39629458

LUFT: A Low-frequency Ultrasound Tomography System Designed for Lung Imaging

Overview
Journal IEEE Sens J
Date 2024 Dec 4
PMID 39629458
Authors
Affiliations
Soon will be listed here.
Abstract

Pulmonary imaging with ultrasound in the conventional MHz range suffers from significant artifacts, as the high frequency acoustic waves primarily reflect off of the lung pleura with little to no penetration through the lung tissue. Furthermore, B-mode ultrasound images are difficult to interpret and require a skilled technician to obtain. Motivated by the finding that acoustic frequencies in the kHz penetrate lung tissue, a low-frequency tomographic ultrasound system is presented. A Verasonics Vantage 64 low-frequency ultrasound system is programmed to work with a novel low-frequency Tonpilz transducers set arranged in a circular array on a belt. After signal processing, a time-of-flight (TOF) tomographic reconstruction algorithm with refraction correction is applied to estimate the sound speed in the plane of the transducer array. Data were collected on experimental phantoms made of ballistic gel containing targets of varying sound speeds, and reconstructions TOF were computed. Results demonstrate that the low-frequency ultrasound tomography system effectively detects targets in an experimental phantom with the ability to resolve multiple targets and distinguish between targets of high and low sound speed compared to the background medium.

Citing Articles

Imaging of ventilation and lung injury with low-frequency tomographic ultrasound.

Pigatto A, Furuie S, Cardenas D, Rezende M, Lima R, Mueller J Med Phys. 2024; 51(12):9138-9154.

PMID: 39312493 PMC: 11656285. DOI: 10.1002/mp.17421.

References
1.
Domenighetti G, Maggiorini M . Electrical impedance tomography to guide ventilation in ALI-ARDS patients: a research tool for zealous physiologists or an imminent support for the real world intensivist?. Minerva Anestesiol. 2010; 76(12):986-8. View

2.
Gattinoni L, Caironi P, Cressoni M, Chiumello D, Ranieri V, Quintel M . Lung recruitment in patients with the acute respiratory distress syndrome. N Engl J Med. 2006; 354(17):1775-86. DOI: 10.1056/NEJMoa052052. View

3.
Aldrich J . Basic physics of ultrasound imaging. Crit Care Med. 2007; 35(5 Suppl):S131-7. DOI: 10.1097/01.CCM.0000260624.99430.22. View

4.
Lindgren S, Odenstedt H, Olegard C, Sondergaard S, Lundin S, Stenqvist O . Regional lung derecruitment after endotracheal suction during volume- or pressure-controlled ventilation: a study using electric impedance tomography. Intensive Care Med. 2006; 33(1):172-80. DOI: 10.1007/s00134-006-0425-x. View

5.
Meier T, Luepschen H, Karsten J, Leibecke T, Grossherr M, Gehring H . Assessment of regional lung recruitment and derecruitment during a PEEP trial based on electrical impedance tomography. Intensive Care Med. 2007; 34(3):543-50. DOI: 10.1007/s00134-007-0786-9. View