Aluminum Resistance in Plants: A Critical Review Focusing on STOP1

Overview

Journal Plant Commun

Specialty Biology

Date 2024 Dec 4

PMID 39628052

Authors

Chao-Feng Huang

Yingtang Ma

Affiliations

Soon will be listed here.

Abstract

Aluminum (Al) toxicity poses a significant challenge for plant production on acidic soils, which constitute approximately 30% of the world's ice-free land. To combat Al toxicity, plants have evolved both external and internal detoxification mechanisms. The zinc-finger transcription factor STOP1 (SENSITIVE TO PROTON RHIZOTOXICITY 1) plays a critical and conserved role in Al resistance by inducing genes involved in both external exclusion and internal detoxification mechanisms. Recent studies have uncovered multiple layers of post-transcriptional regulation of STOP1 and have elucidated mechanisms by which plants sense Al and activate signaling cascades that regulate STOP1 function. This review offers a comprehensive overview of the mechanisms through which STOP1 and its homologs confer Al resistance in plants, with a particular focus on Arabidopsis thaliana and rice. Additionally, we discuss recent advances and future perspectives in understanding the post-transcriptional regulation of STOP1, as well as the Al sensing and signaling pathways upstream of STOP1.

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