Plant Microbiota Feedbacks Through Dose-responsive Expression of General Non-self Response Genes

Overview

Journal Nat Plants

Specialties Biology
Genetics

Date 2024 Dec 3

PMID 39627368

Authors

Andreas Keppler

Michelle Roulier

Sebastian Pfeilmeier

Gabriella C Petti

Anna Sintsova

Benjamin A Maier

Miriam Bortfeld-Miller

Shinichi Sunagawa

Cyril Zipfel

Julia A Vorholt

Affiliations

Soon will be listed here.

Abstract

The ability of plants to perceive and react to biotic and abiotic stresses is critical for their health. We recently identified a core set of genes consistently induced by members of the leaf microbiota, termed general non-self response (GNSR) genes. Here we show that GNSR components conversely impact leaf microbiota composition. Specific strains that benefited from this altered assembly triggered strong plant responses, suggesting that the GNSR is a dynamic system that modulates colonization by certain strains. Examination of the GNSR to live and inactivated bacteria revealed that bacterial abundance, cellular composition and exposure time collectively determine the extent of the host response. We link the GNSR to pattern-triggered immunity, as diverse microbe- or danger-associated molecular patterns cause dynamic GNSR gene expression. Our findings suggest that the GNSR is the result of a dose-responsive perception and signalling system that feeds back to the leaf microbiota and contributes to the intricate balance of plant-microbiome interactions.

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