Clinical Features and Progress in Diagnosis and Treatment of Amyotrophic Lateral Sclerosis
Overview
Overview
Journal
Ann Med
Publisher
Informa Healthcare
Specialty
General Medicine
Date
2024 Dec 3
PMID
39624969
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease of the central nervous system. Despite a large number of studies, the current prognosis of ALS is still not ideal. This article briefly describes the clinical features including epidemiology, genetic structure and clinical manifestations, as well as the progress of new diagnostic criteria and treatment of ALS. Meanwhile, we also discussed further both developments and improvements to enhance understanding and accelerating the introduction of the effective treatments of ALS.
References
1.
Babu S, Pioro E, Li J, Li Y
. Optimizing muscle selection for electromyography in amyotrophic lateral sclerosis. Muscle Nerve. 2016; 56(1):36-44.
DOI: 10.1002/mus.25444.
View
2.
Shi J, Qin X, Chang X, Wang H, Guo J, Zhang W
. Neurofilament markers in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosis. J Cell Mol Med. 2021; 26(2):583-587.
PMC: 8743649.
DOI: 10.1111/jcmm.17100.
View
3.
Phukan J, Pender N, Hardiman O
. Cognitive impairment in amyotrophic lateral sclerosis. Lancet Neurol. 2007; 6(11):994-1003.
DOI: 10.1016/S1474-4422(07)70265-X.
View
4.
Brodovitch A, Boucraut J, Delmont E, Parlanti A, Grapperon A, Attarian S
. Combination of serum and CSF neurofilament-light and neuroinflammatory biomarkers to evaluate ALS. Sci Rep. 2021; 11(1):703.
PMC: 7803734.
DOI: 10.1038/s41598-020-80370-6.
View
5.
Beeldman E, Govaarts R, de Visser M, Klein Twennaar M, van der Kooi A, van den Berg L
. Progression of cognitive and behavioural impairment in early amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry. 2020; 91(7):779-780.
PMC: 7361007.
DOI: 10.1136/jnnp-2020-322992.
View