The Genetics of Pain

Overview

Journal BJA Educ

Publisher Elsevier

Specialty Anesthesiology

Date 2024 Dec 2

PMID 39620104

Authors

J J Cox

D Srivastava

Affiliations

Soon will be listed here.

References

Young E, Lariviere W, Belfer I . Genetic basis of pain variability: recent advances. J Med Genet. 2011; 49(1):1-9. PMC: 3821734. DOI: 10.1136/jmedgenet-2011-100386. View

Xiao R, Boehnke M . Quantifying and correcting for the winner's curse in genetic association studies. Genet Epidemiol. 2009; 33(5):453-62. PMC: 2706290. DOI: 10.1002/gepi.20398. View

OConnor E, Simpson B, Houlden H, Vandrovcova J, Matharu M . Prevalence of familial cluster headache: a systematic review and meta-analysis. J Headache Pain. 2020; 21(1):37. PMC: 7183702. DOI: 10.1186/s10194-020-01101-w. View

Denk F, McMahon S, Tracey I . Pain vulnerability: a neurobiological perspective. Nat Neurosci. 2014; 17(2):192-200. DOI: 10.1038/nn.3628. View

Parisien M, Lima L, Dagostino C, El-Hachem N, Drury G, Grant A . Acute inflammatory response via neutrophil activation protects against the development of chronic pain. Sci Transl Med. 2022; 14(644):eabj9954. PMC: 10317000. DOI: 10.1126/scitranslmed.abj9954. View

Carville S, Constanti M, Kosky N, Stannard C, Wilkinson C . Chronic pain (primary and secondary) in over 16s: summary of NICE guidance. BMJ. 2021; 373:n895. DOI: 10.1136/bmj.n895. View

Grond S, Sablotzki A . Clinical pharmacology of tramadol. Clin Pharmacokinet. 2004; 43(13):879-923. DOI: 10.2165/00003088-200443130-00004. View

Lischka A, Lassuthova P, Cakar A, Record C, Van Lent J, Baets J . Genetic pain loss disorders. Nat Rev Dis Primers. 2022; 8(1):41. DOI: 10.1038/s41572-022-00365-7. View

Crews K, Gaedigk A, Dunnenberger H, Leeder J, Klein T, Caudle K . Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 update. Clin Pharmacol Ther. 2014; 95(4):376-82. PMC: 3975212. DOI: 10.1038/clpt.2013.254. View

10.

Hoftun G, Romundstad P, Rygg M . Association of parental chronic pain with chronic pain in the adolescent and young adult: family linkage data from the HUNT Study. JAMA Pediatr. 2013; 167(1):61-9. DOI: 10.1001/jamapediatrics.2013.422. View

11.

Habib A, Okorokov A, Hill M, Bras J, Lee M, Li S . Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity. Br J Anaesth. 2019; 123(2):e249-e253. PMC: 6676009. DOI: 10.1016/j.bja.2019.02.019. View

12.

Hocking L, Morris A, Dominiczak A, Porteous D, Smith B . Heritability of chronic pain in 2195 extended families. Eur J Pain. 2012; 16(7):1053-63. DOI: 10.1002/j.1532-2149.2011.00095.x. View

13.

Kingwell K . Nav1.7 withholds its pain potential. Nat Rev Drug Discov. 2019; . DOI: 10.1038/d41573-019-00065-0. View

14.

Tavares-Ferreira D, Shiers S, Ray P, Wangzhou A, Jeevakumar V, Sankaranarayanan I . Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors. Sci Transl Med. 2022; 14(632):eabj8186. PMC: 9272153. DOI: 10.1126/scitranslmed.abj8186. View

15.

Siletti K, Hodge R, Mossi Albiach A, Lee K, Ding S, Hu L . Transcriptomic diversity of cell types across the adult human brain. Science. 2023; 382(6667):eadd7046. DOI: 10.1126/science.add7046. View

16.

Gerhard G, Kaniper S, Paynton B . Fentanyl overdoses and pharmacogenetics. Pharmacogenet Genomics. 2019; 30(1):5-8. DOI: 10.1097/FPC.0000000000000389. View

17.

Zorina-Lichtenwalter K, Meloto C, Khoury S, Diatchenko L . Genetic predictors of human chronic pain conditions. Neuroscience. 2016; 338:36-62. DOI: 10.1016/j.neuroscience.2016.04.041. View

18.

Kent M, Tighe P, Belfer I, Brennan T, Bruehl S, Brummett C . The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions. Pain Med. 2017; 18(5):947-958. PMC: 5431381. DOI: 10.1093/pm/pnx019. View

19.

M Moreno A, Aleman F, Catroli G, Hunt M, Hu M, Dailamy A . Long-lasting analgesia via targeted in situ repression of Na1.7 in mice. Sci Transl Med. 2021; 13(584). PMC: 8830379. DOI: 10.1126/scitranslmed.aay9056. View

20.

Kumar S, Kundra P, Ramsamy K, Surendiran A . Pharmacogenetics of opioids: a narrative review. Anaesthesia. 2019; 74(11):1456-1470. DOI: 10.1111/anae.14813. View