Revolutionizing Eye Care: Exploring the Potential of Microneedle Drug Delivery

Overview

Journal Pharmaceutics

Publisher MDPI

Date 2024 Nov 27

PMID 39598522

Authors

Satish Rojekar

Swapnali Parit

Amol D Gholap

Ajit Manchare

Sopan N Nangare

Navnath Hatvate

Vrashabh V Sugandhi

Keshav Raj Paudel

Rahul G Ingle

Affiliations

Soon will be listed here.

Abstract

Microneedle technology revolutionizes ocular drug delivery by addressing challenges in treating ocular diseases. This review explores its potential impact, recent advancements, and clinical uses. This minimally invasive technique offers precise control of drug delivery to the eye, with various microneedle types showing the potential to penetrate barriers in the cornea and sclera, ensuring effective drug delivery. Recent advancements have improved safety and efficacy, offering sustained and controlled drug delivery for conditions like age-related macular degeneration and glaucoma. While promising, challenges such as regulatory barriers and long-term biocompatibility persist. Overcoming these through interdisciplinary research is crucial. Ultimately, microneedle drug delivery presents a revolutionary method with the potential to significantly enhance ocular disease treatment, marking a new era in eye care.

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