Emerging Functions of Protein Tyrosine Phosphatases in Plants

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2024 Nov 27

PMID 39596119

Authors

Jing Xin

Chuanling Li

Xiaoqian Liu

Xueke Shi

Yu Sun

Jian-Xiu Shang

Affiliations

Soon will be listed here.

Abstract

Reversible protein phosphorylation, known as the "switch" of the cell, is controlled by protein kinases (PKs) and protein phosphatases (PPs). Based on substrate specificity, PPs are classified into protein serine/threonine phosphatases and protein tyrosine phosphatases (PTPs). PTPs can dephosphorylate phosphotyrosine and phosphoserine/phosphothreonine. In plants, PTPs monitor plant physiology, growth, and development. This review summarizes an overview of the PTPs' classification and describes how PTPs regulate various plant processes, including plant growth and development, plant hormone responses, and responses to abiotic and biotic stresses. Then, future research directions on the PTP family in plants are discussed. This summary will serve as a reference for researchers studying PTPs in plants.

References

Ayatollahi Z, Kazanaviciute V, Shubchynskyy V, Kvederaviciute K, Schwanninger M, Rozhon W . Dual control of MAPK activities by AP2C1 and MKP1 MAPK phosphatases regulates defence responses in Arabidopsis. J Exp Bot. 2022; 73(8):2369-2384. PMC: 9015810. DOI: 10.1093/jxb/erac018. View

Knetsch M, Wang M, Snaar-Jagalska B, Heimovaara-Dijkstra S . Abscisic Acid Induces Mitogen-Activated Protein Kinase Activation in Barley Aleurone Protoplasts. Plant Cell. 1996; 8(6):1061-1067. PMC: 161161. DOI: 10.1105/tpc.8.6.1061. View

Song W, Hu L, Ma Z, Yang L, Li J . Importance of Tyrosine Phosphorylation in Hormone-Regulated Plant Growth and Development. Int J Mol Sci. 2022; 23(12). PMC: 9224382. DOI: 10.3390/ijms23126603. View

Zhou H, Shi H, Yang Y, Feng X, Chen X, Xiao F . Insights into plant salt stress signaling and tolerance. J Genet Genomics. 2023; 51(1):16-34. DOI: 10.1016/j.jgg.2023.08.007. View

Lee K, Song E, Kim H, Yoo J, Han H, Jung M . Regulation of MAPK phosphatase 1 (AtMKP1) by calmodulin in Arabidopsis. J Biol Chem. 2008; 283(35):23581-8. PMC: 3259760. DOI: 10.1074/jbc.M801549200. View

He H, Su J, Shu S, Zhang Y, Ao Y, Liu B . Two homologous putative protein tyrosine phosphatases, OsPFA-DSP2 and AtPFA-DSP4, negatively regulate the pathogen response in transgenic plants. PLoS One. 2012; 7(4):e34995. PMC: 3325911. DOI: 10.1371/journal.pone.0034995. View

Strader L, Monroe-Augustus M, Bartel B . The IBR5 phosphatase promotes Arabidopsis auxin responses through a novel mechanism distinct from TIR1-mediated repressor degradation. BMC Plant Biol. 2008; 8:41. PMC: 2374786. DOI: 10.1186/1471-2229-8-41. View

Xin J, Li C, Ning K, Qin Y, Shang J, Sun Y . AtPFA-DSP3, an atypical dual-specificity protein tyrosine phosphatase, affects salt stress response by modulating MPK3 and MPK6 activity. Plant Cell Environ. 2021; 44(5):1534-1548. DOI: 10.1111/pce.14002. View

Ulm R, Ichimura K, Mizoguchi T, Peck S, Zhu T, Wang X . Distinct regulation of salinity and genotoxic stress responses by Arabidopsis MAP kinase phosphatase 1. EMBO J. 2002; 21(23):6483-93. PMC: 136950. DOI: 10.1093/emboj/cdf646. View

10.

Liu R, Liu Y, Ye N, Zhu G, Chen M, Jia L . AtDsPTP1 acts as a negative regulator in osmotic stress signalling during Arabidopsis seed germination and seedling establishment. J Exp Bot. 2014; 66(5):1339-53. PMC: 4339596. DOI: 10.1093/jxb/eru484. View

11.

Lee J, Ellis B . Arabidopsis MAPK phosphatase 2 (MKP2) positively regulates oxidative stress tolerance and inactivates the MPK3 and MPK6 MAPKs. J Biol Chem. 2007; 282(34):25020-9. DOI: 10.1074/jbc.M701888200. View

12.

Tang Q, Guittard-Crilat E, Maldiney R, Habricot Y, Miginiac E, Bouly J . The mitogen-activated protein kinase phosphatase PHS1 regulates flowering in Arabidopsis thaliana. Planta. 2016; 243(4):909-23. DOI: 10.1007/s00425-015-2447-5. View

13.

Gonzalez E . Drought Stress Tolerance in Plants. Int J Mol Sci. 2023; 24(7). PMC: 10095095. DOI: 10.3390/ijms24076562. View

14.

Brautigan D . Protein Ser/Thr phosphatases--the ugly ducklings of cell signalling. FEBS J. 2012; 280(2):324-45. DOI: 10.1111/j.1742-4658.2012.08609.x. View

15.

Collinge D, Jensen B, Jorgensen H . Fungal endophytes in plants and their relationship to plant disease. Curr Opin Microbiol. 2022; 69:102177. DOI: 10.1016/j.mib.2022.102177. View

16.

MacRobbie E . Evidence for a role for protein tyrosine phosphatase in the control of ion release from the guard cell vacuole in stomatal closure. Proc Natl Acad Sci U S A. 2002; 99(18):11963-8. PMC: 129377. DOI: 10.1073/pnas.172360399. View

17.

Nemoto K, Takemori N, Seki M, Shinozaki K, Sawasaki T . Members of the Plant CRK Superfamily Are Capable of Trans- and Autophosphorylation of Tyrosine Residues. J Biol Chem. 2015; 290(27):16665-77. PMC: 4505418. DOI: 10.1074/jbc.M114.617274. View

18.

Wang W, Hostettler C, Damberger F, Kossmann J, Lloyd J, Zeeman S . Modification of Cassava Root Starch Phosphorylation Enhances Starch Functional Properties. Front Plant Sci. 2018; 9:1562. PMC: 6218586. DOI: 10.3389/fpls.2018.01562. View

19.

Sharma A, Abrahamian P, Carvalho R, Choudhary M, Paret M, Vallad G . Future of Bacterial Disease Management in Crop Production. Annu Rev Phytopathol. 2022; 60:259-282. DOI: 10.1146/annurev-phyto-021621-121806. View

20.

Dautel R, Wu X, Heunemann M, Schulze W, Harter K . The Sensor Histidine Kinases AHK2 and AHK3 Proceed into Multiple Serine/Threonine/Tyrosine Phosphorylation Pathways in Arabidopsis thaliana. Mol Plant. 2015; 9(1):182-186. DOI: 10.1016/j.molp.2015.10.002. View