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Investigation of Sex Determination in Starry Flounder ( ) Reveals Sex Chromosome Evolution in Pleuronectiformes and Identifies a Sex-specific Marker

Overview
Journal Zool Res
Publisher Science Press
Date 2024 Nov 21
PMID 39572017
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Abstract

The identification of sex chromosomes is fundamental for exploring the mechanism and evolution of sex determination. , a species exhibiting clear sexual dimorphism and homomorphic chromosome pairs, has received limited research concerning its sex determination mechanisms. Clarifying the sex chromosome of will enhance our understanding of sex chromosome evolution in Pleuronectiformes. This study employed whole-genome resequencing to investigate the sex chromosome and sex determination system in . Notably, Chr23 was identified as the sex chromosome in , with the sex-determining region (SDR) occupying 48.1% of the chromosome and featuring an XX/XY system. Sex chromosome turnover was observed within Pleuronectiformes, with , , and sharing a common ancestral karyotype. No inversions were detected within the SDR of , although chromosomal rearrangements between sex chromosomes and autosomes were identified. Additionally, a sex-specific marker for was ascertained, enabling genetic sex identification, with significant implications for improving breeding programs and aquaculture practices.

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