Multiple-site Decontamination in Critically Ill Patients Requires Careful Implementation
Overview
Affiliations
The EPIC III study showed that 52% of patients admitted to the intensive care unit (ICU) have infectious diseases and that the incidence of ICU-acquired infections is increasing, leading to longer ICU stays and higher mortality rates. Multiple-site decontamination, a type of selective decontamination program, has been associated with a reduction in the incidence of ICU-acquired infection and decreased mortality rates in some critically ill patients. However, the standardized implementation and actual effectiveness of multiple-site decontamination require further investigation.
Editorial: Infections in the intensive care unit, volume II.
Wang L, Lin B, Zhang Z, Yu Y Front Med (Lausanne). 2025; 12:1550303.
PMID: 39911874 PMC: 11795514. DOI: 10.3389/fmed.2025.1550303.