» Articles » PMID: 39559718

Prevalence of Respiratory Syncytial Virus Among Children Under 5 Years of Age in Sub-Saharan Africa

Overview
Specialty Pediatrics
Date 2024 Nov 19
PMID 39559718
Authors
Affiliations
Soon will be listed here.
Abstract

. Pneumonia and bronchiolitis are common childhood illnesses caused by the respiratory syncytial virus. A systematic analysis of published epidemiological data in sub-Saharan African children under the age of 5 was conducted. . To retrieve literature, electronic databases, indexing services, and directories such as PubMed/MEDLINE, Scopus, EMBASE (Elsevier), Google Scholar, and Worldcat were utilized. Data from the included studies were extracted after screening and eligibility evaluation. . The pooled prevalence rate of respiratory syncytial virus was 21% (95% CI: 17, 25). Subgroup analysis based on participants' ages showed that, prevalence was highest in children <6 months (32%). High prevalence was also found in children who were hospitalized (27%), children co-infected with HIV (28%), and children co-infected with bacteria respiratory pathogens (22%). . The prevalence of respiratory syncytial virus infection was high in children in sub-Saharan African countries. Therefore, it should be prioritized as a major health problem.

References
1.
Weldetsadik A, Riedel F . Respiratory syncytial virus in severe lower respiratory infections in previously healthy young Ethiopian infants. BMC Pediatr. 2021; 21(1):201. PMC: 8080344. DOI: 10.1186/s12887-021-02675-3. View

2.
Seidu A, Dickson K, Ahinkorah B, Amu H, Darteh E, Kumi-Kyereme A . Prevalence and determinants of Acute Lower Respiratory Infections among children under-five years in sub-Saharan Africa: Evidence from demographic and health surveys. SSM Popul Health. 2019; 8:100443. PMC: 6614699. DOI: 10.1016/j.ssmph.2019.100443. View

3.
Shi T, Balsells E, Wastnedge E, Singleton R, Rasmussen Z, Zar H . Risk factors for respiratory syncytial virus associated with acute lower respiratory infection in children under five years: Systematic review and meta-analysis. J Glob Health. 2015; 5(2):020416. PMC: 4676580. DOI: 10.7189/jogh.05.020416. View

4.
Hall C, Simoes E, Anderson L . Clinical and epidemiologic features of respiratory syncytial virus. Curr Top Microbiol Immunol. 2013; 372:39-57. DOI: 10.1007/978-3-642-38919-1_2. View

5.
Blau D, Baillie V, Els T, Mahtab S, Mutevedzi P, Keita A . Deaths Attributed to Respiratory Syncytial Virus in Young Children in High-Mortality Rate Settings: Report from Child Health and Mortality Prevention Surveillance (CHAMPS). Clin Infect Dis. 2021; 73(Suppl_3):S218-S228. PMC: 8411256. DOI: 10.1093/cid/ciab509. View