Phenotypic and Genomic Characterization of ST11-K1 CR-hvKP with Highly Homologous -bearing Plasmids in China

Overview

Journal mSystems

Publisher American Society for Microbiology

Specialty Microbiology

Date 2024 Nov 18

PMID 39555910

Authors

Yu-Ling Han

Hua Wang

Hong-Zhe Zhu

Ying-Ying Lv

Wen Zhao

Yan-Yan Wang

Jian-Xun Wen

Zhi-De Hu

Jun-Rui Wang

Wen-Qi Zheng

Affiliations

Soon will be listed here.

Abstract

Importance: We reported seven CR-hvKP strains all carried a highly homologous integrated IncFⅡ-resistant plasmid, and two strains harbored virulence plasmids. Conjugation experiments confirmed the transferability of these plasmids, indicating a potential for resistance spread. Phylogenetic analysis clarified the relationship among the CR-hvKP isolates. This study provides insights into the phenotypic and genomic characteristics of seven ST11-K1 CR-hvKP strains. The high prevalence and potential for local outbreaks emphasize the need for effective control measures.

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