Effects of Dimethylsulfoxide on Membrane Currents of Neuroblastoma X Glioma Hybrid Cell

Overview

Journal Biochim Biophys Acta

Specialties Biochemistry
Biophysics

Date 1986 Apr 14

PMID 3955050

Citations 7

Authors

P Jourdon

J M Dubois

Affiliations

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Abstract

Giga-ohm seal whole cell recording technique was used to examine ionic currents changes induced by dimethylsulfoxide (DMSO) in neuroblastoma X glioma hybrid NG 108-15 cells. DMSO (0.5-1%) reversible blocks sodium, potassium and calcium currents and shifts by about 6 mV the sodium inactivation curve towards more negative voltages.

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