The Prevalence of Traumatic Exposure in Women with Premenstrual Dysphoric Disorder (PMDD): a Systematic Review

Overview

Journal Arch Womens Ment Health

Publisher Springer

Specialties Gynecology & Obstetrics
Psychiatry
Psychology

Date 2024 Nov 15

PMID 39546002

Authors

Jasleen Kaur Grewal

Eveline Mu

Qi Li

Elizabeth H X Thomas

Jayashri Kulkarni

Leo Chen

Affiliations

Soon will be listed here.

Abstract

Background And Purpose: Premenstrual dysphoric disorder (PMDD) is a debilitating illness that affects 3-8% of women worldwide. There are multiple factors underlying the aetiology of PMDD, ranging from neuroendocrine changes to psychosocial factors such as exposure to trauma. This systematic review aims to assess the prevalence of traumatic exposure in women with PMDD.

Methods: A literature search of MEDLINE, EMBASE and PsycInfo was conducted following PRISMA guidelines. Of the 369 studies identified for abstract and full-text screening, 27 were included for review and 16 studies for the quantitative calculation of average prevalence and 95% confidence intervals. Data extracted included study details, sampling details, demographic details, type of traumatic exposure reported, diagnostic tools used, the prevalence of PMDD (total) and the prevalence of self-reported traumatic exposure in PMDD patients.

Results: The reported prevalence of traumatic exposure in PMDD ranged from 18.03 to 90.5%. Using a random effects model, the pooled prevalence was 61% (95%CI, 46-74%). The level of heterogeneity (I) was 95%, showing considerable variability in the data. Amongst only those studies with a control group, it was shown that those with PMDD are 1.99 times more likely to have a history of traumatic exposure than those without PMDD.

Conclusion: Our findings suggest that a history of traumatic exposure is highly represented in women living with PMDD. Trauma exposure may be a risk factor for PMDD and could inform this condition's aetiology. A trauma-informed approach should be considered when assessing and managing women presenting with PMDD.

References

Alwafa R, Badrasawi M, Haj Hamad R . Prevalence of premenstrual syndrome and its association with psychosocial and lifestyle variables: a cross-sectional study from Palestine. BMC Womens Health. 2021; 21(1):233. PMC: 8178841. DOI: 10.1186/s12905-021-01374-6. View

Azoulay M, Reuveni I, Dan R, Goelman G, Segman R, Kalla C . Childhood Trauma and Premenstrual Symptoms: The Role of Emotion Regulation. Child Abuse Negl. 2020; 108:104637. DOI: 10.1016/j.chiabu.2020.104637. View

Beddig T, Reinhard I, Kuehner C . Stress, mood, and cortisol during daily life in women with Premenstrual Dysphoric Disorder (PMDD). Psychoneuroendocrinology. 2019; 109:104372. DOI: 10.1016/j.psyneuen.2019.104372. View

Born L, Phillips S, Steiner M, Soares C . [Trauma & the reproductive lifecycle in women]. Braz J Psychiatry. 2005; 27 Suppl 2:S65-72. DOI: 10.1590/s1516-44462005000600006. View

Bunevicius R, Hinderliter A, Light K, Leserman J, Pedersen C, Girdler S . Histories of sexual abuse are associated with differential effects of clonidine on autonomic function in women with premenstrual dysphoric disorder. Biol Psychol. 2005; 69(3):281-96. DOI: 10.1016/j.biopsycho.2004.08.002. View

Eisenlohr-Moul T, Rubinow D, Schiller C, Johnson J, Leserman J, Girdler S . Histories of abuse predict stronger within-person covariation of ovarian steroids and mood symptoms in women with menstrually related mood disorder. Psychoneuroendocrinology. 2016; 67:142-52. PMC: 4811338. DOI: 10.1016/j.psyneuen.2016.01.026. View

Epperson C, Steiner M, Hartlage S, Eriksson E, Schmidt P, Jones I . Premenstrual dysphoric disorder: evidence for a new category for DSM-5. Am J Psychiatry. 2012; 169(5):465-75. PMC: 3462360. DOI: 10.1176/appi.ajp.2012.11081302. View

Girdler S, Pedersen C, Straneva P, Leserman J, Stanwyck C, Benjamin S . Dysregulation of cardiovascular and neuroendocrine responses to stress in premenstrual dysphoric disorder. Psychiatry Res. 1998; 81(2):163-78. DOI: 10.1016/s0165-1781(98)00074-2. View

Girdler S, Sherwood A, Hinderliter A, Leserman J, Costello N, Straneva P . Biological correlates of abuse in women with premenstrual dysphoric disorder and healthy controls. Psychosom Med. 2003; 65(5):849-56. DOI: 10.1097/01.psy.0000088593.38201.cd. View

10.

Girdler S, Thompson K, Light K, Leserman J, Pedersen C, Prange Jr A . Historical sexual abuse and current thyroid axis profiles in women with premenstrual dysphoric disorder. Psychosom Med. 2004; 66(3):403-10. DOI: 10.1097/01.psy.0000127690.38525.ab. View

11.

Girdler S, Leserman J, Bunevicius R, Klatzkin R, Pedersen C, Light K . Persistent alterations in biological profiles in women with abuse histories: influence of premenstrual dysphoric disorder. Health Psychol. 2007; 26(2):201-13. PMC: 2750879. DOI: 10.1037/0278-6133.26.2.201. View

12.

Hantsoo L, Epperson C . Allopregnanolone in premenstrual dysphoric disorder (PMDD): Evidence for dysregulated sensitivity to GABA-A receptor modulating neuroactive steroids across the menstrual cycle. Neurobiol Stress. 2020; 12:100213. PMC: 7231988. DOI: 10.1016/j.ynstr.2020.100213. View

13.

Hong J, Park S, Wang H, Chang S, Sohn J, Jeon H . Prevalence, correlates, comorbidities, and suicidal tendencies of premenstrual dysphoric disorder in a nationwide sample of Korean women. Soc Psychiatry Psychiatr Epidemiol. 2012; 47(12):1937-45. DOI: 10.1007/s00127-012-0509-6. View

14.

Hornor G . Childhood trauma exposure and toxic stress: what the PNP needs to know. J Pediatr Health Care. 2015; 29(2):191-8. DOI: 10.1016/j.pedhc.2014.09.006. View

15.

Klatzkin R, Morrow A, Light K, Pedersen C, Girdler S . Associations of histories of depression and PMDD diagnosis with allopregnanolone concentrations following the oral administration of micronized progesterone. Psychoneuroendocrinology. 2006; 31(10):1208-19. DOI: 10.1016/j.psyneuen.2006.09.002. View

16.

Kulkarni J, Leyden O, Gavrilidis E, Thew C, Thomas E . The prevalence of early life trauma in premenstrual dysphoric disorder (PMDD). Psychiatry Res. 2022; 308:114381. DOI: 10.1016/j.psychres.2021.114381. View

17.

Leserman J, Drossman D, Li Z, Toomey T, Nachman G, Glogau L . Sexual and physical abuse history in gastroenterology practice: how types of abuse impact health status. Psychosom Med. 1996; 58(1):4-15. DOI: 10.1097/00006842-199601000-00002. View

18.

Lo C, Mertz D, Loeb M . Newcastle-Ottawa Scale: comparing reviewers' to authors' assessments. BMC Med Res Methodol. 2014; 14:45. PMC: 4021422. DOI: 10.1186/1471-2288-14-45. View

19.

Mu E, Thomas E, Kulkarni J . Menstrual Cycle in Trauma-Related Disorders: A Mini-Review. Front Glob Womens Health. 2022; 3:910220. PMC: 9189376. DOI: 10.3389/fgwh.2022.910220. View

20.

Perkonigg A, Yonkers K, Pfister H, Lieb R, Wittchen H . Risk factors for premenstrual dysphoric disorder in a community sample of young women: the role of traumatic events and posttraumatic stress disorder. J Clin Psychiatry. 2004; 65(10):1314-22. DOI: 10.4088/jcp.v65n1004. View