A Review on Targeted Temperature Management for Cardiac Arrest and Traumatic Brain Injury

Overview

Journal Front Neurosci

Date 2024 Nov 15

PMID 39544908

Authors

Hiroshi Ito

Sanae Hosomi

Takeshi Nishida

Youhei Nakamura

Jiro Iba

Hiroshi Ogura

Jun Oda

Affiliations

Soon will be listed here.

Abstract

Therapeutic hypothermia inhibits organ damage by suppressing metabolism, which makes it a therapy of choice for treating various diseases. Specifically, it is often used to treat conditions involving central nervous system disorders where it is expected to positively impact functional prognosis. Although keeping the body temperature at a hypothermic level has been conventionally used, how to manage the body temperature correctly remains a topic of debate. Recently, the concept of temperature management has been proposed to improve the quality of body temperature control and avoid hyperthermia. This review focuses on the effect of temperature on the central nervous system in conditions involving central nervous system disorders and the practice of temperature management in clinical situations.

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