Genome-Wide Identification and Analysis of Gene Family of Carbohydrate-Binding Modules in

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2024 Nov 9

PMID 39519340

Authors

Dongyu Zhai

Deze Xu

Ting Xiang

Yu Zhang

Nianchen Wu

Fuqing Nie

Desuo Yin

Aijun Wang

Affiliations

Soon will be listed here.

Abstract

is a pathogenic basidiomycete fungus that causes foxtail millet kernel smut (FMKS), a devastating grain disease in most foxtail millet growing regions of the world. Carbohydrate-Binding Modules (CBMs) are one of the important families of carbohydrate-active enzymes (CAZymes) in fungi and play a crucial role in fungal growth and development, as well as in pathogen infection. However, there is little information about the CBM family in . Here, 11 CBM members were identified based on complete sequence analysis and functional annotation of the genome of . According to phylogenetic analysis, they were divided into six groups. Gene structure and sequence composition analysis showed that these 11 UcCBM genes exhibit differences in gene structure and protein motifs. Furthermore, several cis-regulatory elements involved in plant hormones were detected in the promoter regions of these UcCBM genes. Gene ontology (GO) enrichment and protein-protein interaction (PPI) analysis showed that UcCBM proteins were involved in carbohydrate metabolism, and multiple partner protein interactions with UcCBM were also detected. The expression of UcCBM genes during infection is further clarified, and the results indicate that several UcCBM genes were induced by infection. These results provide valuable information for elucidating the features of CBMs' family proteins and lay a crucial foundation for further research into their roles in interactions between and foxtail millet.

Citing Articles

Genome-Wide Identification and Analysis of Carbohydrate-Binding Modules in .

Wang Y, Huang Q, Chen X, Li H, Chang J, Zhang Y Int J Mol Sci. 2025; 26(3).

PMID: 39940689 PMC: 11817085. DOI: 10.3390/ijms26030919.

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