Regulatory Components for Bacterial Cell-Free Systems Engineering

Overview

Journal ACS Synth Biol

Publisher American Chemical Society

Specialties Biotechnology
Molecular Biology

Date 2024 Nov 7

PMID 39509282

Authors

Pao-Wan Lee

Sebastian J Maerkl

Affiliations

Soon will be listed here.

Abstract

Cell-free systems are advancing synthetic biology through fast prototyping and modularity. Complex regulatory networks can now be implemented in cell-free systems enabling various applications, such as diagnostic tool development, gene circuit prototyping, and metabolic engineering. As functional complexity increases, the need for regulatory components also grows. This review provides a comprehensive overview of native as well as engineered regulatory components and their use in bacterial cell-free systems.

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