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Molecular Mechanisms of Sulforaphane in Alzheimer's Disease: Insights from an In-silico Study

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Date 2024 Nov 4
PMID 39493676
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Abstract

Supplementary Information: The online version contains supplementary material available at 10.1007/s40203-024-00267-4.

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References
1.
Chang W, Wang Y, Zhu X, Wu C . Genome-Wide Profiling of miRNA and mRNA Expression in Alzheimer's Disease. Med Sci Monit. 2017; 23:2721-2731. PMC: 5467707. DOI: 10.12659/msm.905064. View

2.
Choi S, Singh S . Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent. Cancer Res. 2005; 65(5):2035-43. DOI: 10.1158/0008-5472.CAN-04-3616. View

3.
Chin C, Chen S, Wu H, Ho C, Ko M, Lin C . cytoHubba: identifying hub objects and sub-networks from complex interactome. BMC Syst Biol. 2014; 8 Suppl 4:S11. PMC: 4290687. DOI: 10.1186/1752-0509-8-S4-S11. View

4.
Tian S, Li X, Wang Y, Lu Y . The protective effect of sulforaphane on type II diabetes induced by high-fat diet and low-dosage streptozotocin. Food Sci Nutr. 2021; 9(2):747-756. PMC: 7866575. DOI: 10.1002/fsn3.2040. View

5.
Lee C, Park G, Lee S, Jang J . Attenuation of β-amyloid-induced oxidative cell death by sulforaphane via activation of NF-E2-related factor 2. Oxid Med Cell Longev. 2013; 2013:313510. PMC: 3705986. DOI: 10.1155/2013/313510. View