Microbiological Surveillance Result of Endoscopes After INTERCEPT Foam Spray: a Quasi-experimental Pilot Study in Singapore

Overview

Journal Clin Endosc

Date 2024 Nov 3

PMID 39489603

Authors

Caihong Wang

Rong Zhang

Ruhui Fan

Jiewen Low

Ruochen Du

Xueyun Ma

Congcong Cai

Affiliations

Soon will be listed here.

Abstract

Background/aims: This study aimed to assess the impact of INTERCEPT Foam Spray (IFS) application on delayed endoscope reprocessing through microbiological surveillance culture (MSC).

Methods: A quasi-experimental, matched-comparison pilot study was conducted using gastrointestinal endoscopy. IFS was applied to the endoscopes after precleaning and before reprocessing the next day. An equal number of endoscopes, matched by endoscope type, were subjected to routine reprocessing. The MSC were subjected to high-level disinfection to detect any contamination. Data were analyzed using the chi-square test or Fisher exact test (categorical data) and Student t-test (continuous data).

Results: In total, 150 MSCs were collected from 42 endoscopes. Positive MSCs were observed in 4.0% (4/75) of the sprayed group and 1.3% (1/75) of the control group (95% confidence interval, 30.34-0.31; p>0.05), all of which were contributed by colonoscopes. Colonoscope were more prone to positive MSC (mean difference in percentage, p<0.05). Mean spraying hours were not associated with detected growth (11.7% vs. 13.6%; 95% confidence interval, 1.43 to -5.27; p>0.05), with environmental and skin flora being the primary contaminants.

Conclusions: IFS may be applied when delayed endoscope processing is necessary, but with caution when applied to colonoscopes. However, further research is warranted to verify the result.

Citing Articles

Efficacy of spray flushing in the reprocessing of flexible endoscopes.

Kumar H, Dhali A, Maity R, Biswas J World J Gastrointest Endosc. 2025; 17(1):100298.

PMID: 39850913 PMC: 11752462. DOI: 10.4253/wjge.v17.i1.100298.

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