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Exploration of the Advantages of Targeted Isolation of Deep-sea Microorganisms and Genetically Engineered Strains

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Publisher Springer
Date 2024 Nov 2
PMID 39487272
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Abstract

Oil, mineral processing and environmental restoration can be dangerous processes. Attempts are often made to apply microorganisms to reduce the risks, but the adaptability of terrestrial organisms is often weak. Although genetically engineered strains can improve their environmental adaptability through targeted modification, there are problems such as metabolite accumulation, poor plasmid stability and potential pathogenicity. Screening of extremophiles from the natural environment has become an inevitable choice. The special environment in the deep sea (high pressure, low temperature, low nutrition, high salinity) is a natural place for extremophiles to grow and survive, thus screening of extremophiles from the deep sea is conducive to the green and sustainable development of industry. In this paper, the application status and problems of genetically engineered strains are reviewed based on the microorganisms needed for extreme industry. This paper focuses on the application status and advantages of deep-sea microorganisms. It is found that their advantages are strong adaptability, stable gene, friendly environment, simple and convenient technology (compared with genetic engineering), which has a broad industry processes application prospect. This review broadens the scope of microbial applications.

References
1.
Abdel-Rahman M, Hassan S, Azab M, Mahin A, Gaber M . High Improvement in Lactic Acid Productivity by New Alkaliphilic Bacterium Using Repeated Batch Fermentation Integrated with Increased Substrate Concentration. Biomed Res Int. 2019; 2019:7212870. PMC: 6354166. DOI: 10.1155/2019/7212870. View

2.
Adam N, Perner M . Microbially Mediated Hydrogen Cycling in Deep-Sea Hydrothermal Vents. Front Microbiol. 2018; 9:2873. PMC: 6265342. DOI: 10.3389/fmicb.2018.02873. View

3.
Becker J, Wittmann C . Microbial production of extremolytes - high-value active ingredients for nutrition, health care, and well-being. Curr Opin Biotechnol. 2020; 65:118-128. DOI: 10.1016/j.copbio.2020.02.010. View

4.
Zhang S, Lv H, Cai X, Tang S, Zhong R, Chen L . Effects of the compound extracts of and Georgi on the intestinal microbiota and antioxidant function. Front Microbiol. 2024; 14:1289490. PMC: 10822692. DOI: 10.3389/fmicb.2023.1289490. View

5.
Yin Q, Zhu F, Tang H, Chen X, Liu X, Tang L . Complete genome sequence of marine Roseobacter lineage member Ruegeria sp. YS9 with five plasmids isolated from red algae. Mar Genomics. 2023; 67:100997. DOI: 10.1016/j.margen.2022.100997. View