Impact of Surgeon-Radiation Oncology Dyads in Oral Cavity Cancer Outcomes

Overview

Journal Ann Surg Oncol

Publisher Springer

Specialty Oncology

Date 2024 Oct 29

PMID 39467971

Authors

Jacob Wihlidal

Alex O Esemezie

Shao Hui Huang

Erin Watson

Ralph W Gilbert

John Waldron

Patrick J Gullane

Andrew Hope

Jonathan C Irish

Brian OSullivan

Douglas B Chepeha

John J H Kim

Dale Brown

B C John Cho

Ian J Witterick

Eric Monteiro

Joel C Davies

Jolie Ringash

David P Goldstein

Scott Bratman

Andrew Bayley

John R de Almeida

Timothy C Y Chan

Ali Hosni

Christopher M K L Yao

Affiliations

Soon will be listed here.

Abstract

Background: Multidisciplinary care is paramount in patient-specific decision making, especially as pertaining to oral cavity squamous cell cancer (OCSCC) treatment. Protracted surgery-postoperative-radiation (S-PORT) has a detrimental impact on OCSCC patients' outcomes. This study examined the impact of surgeon-radiation oncologist dyads on the treatment of OCSCC, focusing on S-PORT interval and disease specific outcomes.

Methods: All OCSCC patients treated in a tertiary cancer center between 2009 to 2017 were included. Patients were categorized into "dyad" and "nondyad" groups defined as whether they were treated by a paired surgeon-radiation oncology team with joint multidisciplinary clinic or shared >30% patient volumes. Univariate and multivariate logistic regression were performed to identify factors associated with a prolonged S-PORT time interval (≥8 weeks). Overall survival and locoregional recurrence were estimated and compared.

Results: A total of 444 OCSCC were eligible. Treatment by a dyad was significantly less likely associated with S-PORT ≥ 8 weeks (odds ratio [OR]: 0.65; 95% confidence interval [CI] 0.44-0.96; p = 0.03). Obtaining pre-operative radiation oncology consultation also decreased the S-PORT interval. Advanced T-category and the need for free tissue flap reconstruction increased the likelihood of prolonged S-PORT on univariate but not multivariate analysis. No significant differences were observed in overall survival or locoregional recurrence by dyad status nor S-PORT (p > 0.05).

Conclusions: Surgeon-radiation oncology dyads significantly minimized time from surgery to postoperative radiation in OCSCC. While improvement in overall survival or locoregional recurrence was not observed, these findings support close knit collaborative multidisciplinary treatment care models, including dyad-based care.

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