» Articles » PMID: 39464351

Persistent ENT Manifestations in Individuals Who Recovered from COVID-19: A Systematic Review

Overview
Publisher Thieme
Date 2024 Oct 28
PMID 39464351
Authors
Affiliations
Soon will be listed here.
Abstract

 Long coronavirus disease (COVID) refers to the persistence of symptoms long after the recovery from the acute phase of the illness, and it is due to the interplay of various inflammatory mechanisms. This has led to emergence of new deficits, including otorhinolaryngological symptoms, in patients wo have recovered from COVID. The plethora of otorhinolaryngological symptoms associated with long COVID are tinnitus, sensorineural hearing loss (SNHL), vertigo, nasal congestion, sinonasal discomfort, hyposmia/anosmia, dysgeusia, sore throat, dry cough, dyspnea, dysphagia, and hoarseness of voice.  To evaluate the possible ENT symptoms in patients wo have recovered from COVID and to combine those findings with our experience.  We conducted a search on the PubMed, ENT Cochrane, Web of Science, and Google Scholar databases, and a total of 44 studies were selected for the present review.  Otorhinolaryngological complications such as tinnitus, SNHL, vertigo, nasal congestion, sinonasal discomfort, hyposmia/anosmia, dysgeusia, sore throat, dry cough, dyspnea, dysphagia, and hoarseness of voice have been widely reported among in long-COVID patients.

Citing Articles

Post COVID-19 and Long COVID Symptoms in Otorhinolaryngology-A Narrative Review.

Guntinas-Lichius O, Bitter T, Takes R, Lee V, Saba N, Makitie A J Clin Med. 2025; 14(2).

PMID: 39860512 PMC: 11765628. DOI: 10.3390/jcm14020506.

References
1.
Aasfara J, Hajjij A, Bensouda H, Ouhabi H, Benariba F . A unique association of bifacial weakness, paresthesia and vestibulocochlear neuritis as post-COVID-19 manifestation in pregnant women: a case report. Pan Afr Med J. 2021; 38:30. PMC: 7955605. DOI: 10.11604/pamj.2021.38.30.27646. View

2.
Kang Y, Oh J, Lee J, Small P, Chung K, Song W . Long-COVID severe refractory cough: discussion of a case with 6-week longitudinal cough characterization. Asia Pac Allergy. 2022; 12(2):e19. PMC: 9066079. DOI: 10.5415/apallergy.2022.12.e19. View

3.
Guan W, Ni Z, Hu Y, Liang W, Ou C, He J . Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020; 382(18):1708-1720. PMC: 7092819. DOI: 10.1056/NEJMoa2002032. View

4.
El Kik A, Eid H, Aoun Bacha Z . Post-COVID-19 paradoxical vocal cord movement and dysfunctional dysphonia: A clinical case. Respir Med Case Rep. 2022; 39:101710. PMC: 9287584. DOI: 10.1016/j.rmcr.2022.101710. View

5.
Colafrancesco S, Alessandri C, Conti F, Priori R . COVID-19 gone bad: A new character in the spectrum of the hyperferritinemic syndrome?. Autoimmun Rev. 2020; 19(7):102573. PMC: 7199723. DOI: 10.1016/j.autrev.2020.102573. View