The Development of the Occurrence and Metastasis of Breast Cancer by Single-cell Sequencing

Overview

Journal Cancer Cell Int

Publisher Biomed Central

Date 2024 Oct 27

PMID 39462368

Authors

Man Chen

Mengya Feng

Hai Lei

Dan Mo

Shengnan Ren

Dechun Yang

Affiliations

Soon will be listed here.

Abstract

Breast cancer is currently the most frequent malignant tumor and the leading cause of cancer death among women globally. Although the five-year survival rate for early breast cancer has risen to more than 90%, medication resistance persists in advanced breast cancer and some intractable breast cancer, resulting in a poor prognosis, a high recurrence rate, and a low survival rate. Single-cell sequencing (SCS) is the study of a single cell's gene structure and expression level differences in order to discover unusual molecular subgroups, disease development, and a variety of mechanisms. This review briefly discusses single-cell sequencing and its application, and lists the research on single-cell sequencing in the development and metastasis of breast cancer, in order to bring fresh ideas for the comprehensive treatment of breast cancer.

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