» Articles » PMID: 39460285

HPV Vaccination Coverage in Brazil's State of Paraná: Spatial Distribution and Advances in Public Health

Abstract

To analyze the spatial distribution of HPV vaccination coverage in relation to sociodemographic variables in a state of Southern Brazil. This was an ecological, retrospective study with secondary data from the Department of Information Technology of the Unified Health System/Ministry of Health from 2015 to 2022. The cohort method was used to calculate vaccination coverage. Geographically weighted regression was used for the independent variables. There was a 22.04% reduction in vaccination between the first and second doses. Coverage with the first dose of the vaccine reached 95.17% for the female population, 64.67% for the male population, and 79.57% for both sexes. In 50.62% of cities, coverage exceeded 90% for both sexes. In 80.45% of cities, the recommended coverage for females was achieved. The variable municipal performance was positively significant for the increase in vaccination coverage in 45.45% of the regions for girls, 18.18% for boys, and 36.36% for both sexes. The family health strategy variable was significant in 9.09% of the regions for girls and both sexes. The education variable showed an inverse significance for girls in 40.90%, for boys in 18.18%, and for both sexes in 36.36% of the regions. HPV vaccination declined between the first and second doses, with high first-dose coverage among females and moderate coverage among males. Municipal performance notably impacted coverage, particularly for girls. The family health strategy was relevant in specific regions, while educational factors had a variable effect. Addressing these variables may enhance vaccination coverage and minimize the gap between doses.

References
1.
Falcaro M, Castanon A, Ndlela B, Checchi M, Soldan K, Lopez-Bernal J . The effects of the national HPV vaccination programme in England, UK, on cervical cancer and grade 3 cervical intraepithelial neoplasia incidence: a register-based observational study. Lancet. 2021; 398(10316):2084-2092. DOI: 10.1016/S0140-6736(21)02178-4. View

2.
Cheng E, Atkinson P, Shahani A . Elucidating the spatially varying relation between cervical cancer and socio-economic conditions in England. Int J Health Geogr. 2011; 10:51. PMC: 3305905. DOI: 10.1186/1476-072X-10-51. View

3.
Dos Santos L, Roszkowski I, Pujals C, de Oliveira R, Pelloso F, Pelloso Borghesan D . Comparative Analysis of Mortality due to Breast Cancer and Mammography Uptake in the Federative Units of Brazil-2015 to 2021. Asian Pac J Cancer Prev. 2024; 24(12):4339-4348. PMC: 10909118. DOI: 10.31557/APJCP.2023.24.12.4339. View

4.
Moura L, Codeco C, Luz P . Human papillomavirus (HPV) vaccination coverage in Brazil: spatial and age cohort heterogeneity. Rev Bras Epidemiol. 2020; 24:e210001. DOI: 10.1590/1980-549720210001. View

5.
Feiring B, Laake I, Molden T, Cappelen I, Haberg S, Magnus P . Do parental education and income matter? A nationwide register-based study on HPV vaccine uptake in the school-based immunisation programme in Norway. BMJ Open. 2015; 5(5):e006422. PMC: 4442157. DOI: 10.1136/bmjopen-2014-006422. View