First Detection and Characterization of in the Human Vagina in Two Sequential Samples over a Twelve-Day Interval

Overview

Journal Viruses

Publisher MDPI

Specialty Microbiology

Date 2024 Oct 26

PMID 39459879

Authors

Antonio Charlys da Costa

Tania Regina Tozetto-Mendoza

Endrya do Socorro Foro Ramos

Pietro Bortoletto

Noely Evangelista Ferreira

Layla Honorato

Erick Matheus Garcia Barbosa

Heuder Gustavo Oliveira Paiao

Amanda Fernandes de Souza

Iara M Linhares

Steven D Spandorfer

Elcio Leal

Maria Cassia Mendes-Correa

Steven S Witkin

Affiliations

Soon will be listed here.

Abstract

Background: is a CRESS-DNA virus identified almost exclusively in transient fecal samples from various vertebrate species.

Objective: We evaluated human vaginal samples for the presence and maintenance of .

Methods: Viral metagenomics analysis was performed on vaginal samples collected from 28 apparently healthy women in New York City, USA. Twenty-one of the women provided duplicate samples over a 12-21-day interval.

Results: Phylogenetic analysis identified two samples from the same individual, collected over a twelve-day interval, that were positive for the complete genome. All detected sequence contigs belonged to a single variant of CRESS-DNA.

Conclusions: The continuous presence of in the human vagina over a twelve-day period was identified.

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