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Evaluation of Right Ventricular Mechanics Using Exercise Echocardiography in Asymptomatic Patients with Severe Mitral Stenosis

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Publisher Springer
Specialty Radiology
Date 2024 Oct 25
PMID 39455512
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Abstract

We aimed to evaluate the effect of exercise echocardiography (EE) on Right ventricular (RV) deformation parameters in asymptomatic patients with severe rheumatic mitral stenosis (MS) (mitral valve area ≤ 1.5 cm, stage C) and to determine the relation between symptoms and severity of MS. 38 rheumatic MS patients in stage C underwent EE. 20 Patients were defined; as an exercise intolerance group who couldn't reach a maximum heart rate according to their age during exercise due to developing dyspnea The remaining 18 patients who reached a maximum heart rate without dyspnea were defined; as an exercise tolerance group. RV echocardiographic parameters at baseline and peak exercise were compared between the groups. While RV global strain (RV GLS) (21.02 ± 3.33 vs. 21.92 ± 3.03) and RV free wall longitudinal strain (RV FWLS) (23.41 ± 5.66 vs. 25.08 ± 5.00) at baseline were similar in both groups (P = 0.390 P = 0.343), RV GLS (23.38 ± 4.30 vs. 26.05 ± 3.24) and RV FWLS (24.24 ± 5.78 vs. 28.05 ± 4.62) at peak exercise were reduced in exercise intolerance group (P = 0.040 P = 0.033). The best correlations were found between exercise capacity and RV FWLS at baseline and peak exercise in all MS patients (respectively; r = 0.627 P < 0.001; r = 0.697 P < 0.001). RV mechanics has approved the reliability of EE in patients with asymptomatic patients with severe MS. During exercise RV contractile reserve could diminish in MS patients with stage C who develop dyspnea. Moreover, since our study has a close relationship between exercise capacity and RV mechanics, using RV mechanics during exercise echocardiography may be useful for risk stratification in MS patients with severe MS.

References
1.
Mohan J, Sengupta P, Arora R . Immediate and delayed effects of successful percutaneous transvenous mitral commissurotomy on global right ventricular function in patients with isolated mitral stenosis. Int J Cardiol. 1999; 68(2):217-23. DOI: 10.1016/s0167-5273(98)00358-1. View

2.
Hirata N, Sakakibara T, Shimazaki Y, Watanabe S, Nomura F, Akamatsu H . Preoperative and postoperative right ventricular function during exercise in patients with mitral stenosis. J Thorac Cardiovasc Surg. 1992; 104(4):1029-34. View

3.
Bonow R, Carabello B, Chatterjee K, de Leon Jr A, Faxon D, Freed M . ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing Committee to Revise the 1998 guidelines for the.... J Am Coll Cardiol. 2006; 48(3):e1-148. DOI: 10.1016/j.jacc.2006.05.021. View

4.
Ozdemir A, Tulunay Kaya C, Ozdol C, Candemir B, Turhan S, Dincer I . Two-dimensional longitudinal strain and strain rate imaging for assessing the right ventricular function in patients with mitral stenosis. Echocardiography. 2009; 27(5):525-33. DOI: 10.1111/j.1540-8175.2009.01078.x. View

5.
Tanboga I, Kurt M, Bilen E, Aksakal E, Kaya A, Isik T . Assessment of right ventricular mechanics in patients with mitral stenosis by two-dimensional deformation imaging. Echocardiography. 2012; 29(8):956-61. DOI: 10.1111/j.1540-8175.2012.01738.x. View