The Effect of Histological and Subclinical Chorioamnionitis and Funisitis on Breathing Effort in Premature Infants at Birth: a Retrospective Cohort Study

Overview

Journal Eur J Pediatr

Specialty Pediatrics

Date 2024 Oct 25

PMID 39453483

Authors

Timothy J R Panneflek

Janneke Dekker

Kristel L A M Kuypers

Lotte E van der Meeren

Graeme R Polglase

Stuart B Hooper

Thomas van den Akker

Arjan B Te Pas

Affiliations

Soon will be listed here.

Abstract

Conclusion: HCA + FUN and subclinical HCA + FUN are associated with reduced oxygenation and parameters that reflect breathing effort in premature infants at birth.

What Is Known: • Acute antenatal inflammation, in the form of chorioamnionitis (fetal membranes) and funisitis (umbilical vessels), affects a large proportion of premature infants. • Clinical chorioamnionitis is associated with reduced breathing effort and oxygenation in premature infants at birth.

What Is New: • Histological and subclinical chorioamnionitis and funisitis are associated with reduced breathing effort parameters and oxygenation in premature infants at birth.

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