Hemophagocytic Lymphohistiocytosis in Visceral Leishmaniasis: A Rare Yet Treatable Complication

Overview

Journal Cureus

Specialty Biomedical Engineering

Date 2024 Oct 25

PMID 39449916

Authors

Anupam Varshney

Ranjan Solanki

David Manna

Efren Rodriguez

Vijay K Bindra

Affiliations

Soon will be listed here.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a rare debilitating condition that can be triggered by an infectious cause, often linked to the Epstein-Barr virus (EBV). In this case, we evaluated a patient with pancytopenia. The bone marrow aspiration revealed the presence of amastigotes and active hemophagocytosis, indicating that the HLH was induced by a infection. The patient was treated with lyophilized amphotericin B followed by miltefosine, which effectively resolved the infection and HLH. This case report underscores the presentation and findings of -induced HLH, as well as the successful treatment approach that led to improved patient outcomes.

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