Empyema Caused by Mixed Infection with and in a Patient with Previous Surgery for Oral Carcinoma: A Case Report

Overview

Journal Infect Drug Resist

Publisher Dove Medical Press

Date 2024 Oct 21

PMID 39431214

Authors

Xingxing Zhu

Jialu Chen

Shengjie Wu

Jiling Zeng

Yahong Sun

Xiaohong Wu

Affiliations

Soon will be listed here.

Abstract

Background: The incidence of community-acquired empyema caused by the group (SAG) has been on the rise in the 2020s. To the best of our knowledge, while empyema caused individually by either strain has been reported, there are no reports on empyema caused by concurrent infection with these two strains. Here, we report for the first time empyema caused by concurrent infection with and (both SAG species) in a postoperative patient who had been treated for floor of the mouth carcinoma.

Case Presentation: A 61-year-old male patient who had undergone surgical treatment for floor of the mouth carcinoma 2 year earlier suddenly presented with left-sided chest pain. Chest computed tomography (CT) revealed encapsulated pleural effusion on the left side, which was diagnosed as empyema. Metagenomic next-generation sequencing(mNGS) of the pleural fluid sample indicated mixed infection caused by and . The patient's condition improved about 5 weeks after treatment with thoracic fluid drainage and cephalosporin antibiotics.

Conclusion: This case highlights the possibility of concurrent infection with two SAG strains in patients with empyema. Currently, it is unclear whether there is a definitive relationship between a surgical history of carcinoma of the floor of the mouth and empyema caused by infection with SAG strains. This case could, perhaps, serve as a reference for future related research on the topic.

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