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Alcohol-related Liver Disease: Also a Question of What You Drink?

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Journal Explor Dig Dis
Date 2024 Oct 15
PMID 39404693
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Abstract

Excessive alcohol intake is still among the leading causes of chronic liver diseases. Epidemiological studies suggest that per capita consumption of alcohol from various alcohol beverages e.g., beer, wine, or spirits, differs markedly between different areas of the world. Studies further suggest that different alcoholic beverages may impact the development of alcohol-related liver diseases (ALD) differentially. Specifically, results of several more recent epidemiological studies suggest that consumption of wine and herein especially of red wine may be less harmful in relation to the development of liver diseases than the intake of hard spirits. Results of studies evaluating the effects of beer on the development of ALD in humans are rather contradictory. Here, results of studies assessing the impact of wine, beer, and spirits on the development of ALD as well as possible underlying mechanisms are summarized and discussed.

References
1.
Nelson G, KINARD F, HAY M . Rate of metabolism of ethanol in the mouse. Am J Physiol. 1957; 190(1):169-71. DOI: 10.1152/ajplegacy.1957.190.1.169. View

2.
Hagstrom H, Hemmingsson T, Discacciati A, Andreasson A . Risk Behaviors Associated with Alcohol Consumption Predict Future Severe Liver Disease. Dig Dis Sci. 2019; 64(7):2014-2023. PMC: 6584217. DOI: 10.1007/s10620-019-05509-6. View

3.
Han S, Yang J, Choi K, Kim J, Adhikari K, Lee J . Chemical Analysis of Commercial White Wines and Its Relationship with Consumer Acceptability. Foods. 2022; 11(4). PMC: 8871119. DOI: 10.3390/foods11040603. View

4.
Li H, Borinskaya S, Yoshimura K, Kalina N, Marusin A, Stepanov V . Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variant. Ann Hum Genet. 2009; 73(Pt 3):335-45. PMC: 2846302. DOI: 10.1111/j.1469-1809.2009.00517.x. View

5.
Gutierrez-Escobar R, Aliano-Gonzalez M, Cantos-Villar E . Wine Polyphenol Content and Its Influence on Wine Quality and Properties: A Review. Molecules. 2021; 26(3). PMC: 7866523. DOI: 10.3390/molecules26030718. View