» Articles » PMID: 39400790

Myocardial Extracellular Volume Measurement Using Cardiac Computed Tomography

Overview
Publisher Springer
Specialty Radiology
Date 2024 Oct 14
PMID 39400790
Authors
Affiliations
Soon will be listed here.
Abstract

Myocardial fibrosis is a common endpoint of many cardiac diseases and increasingly recognized as a predictor of heart failure, arrhythmia, and death. Recent studies have utilised cardiac computed tomography (CT) scans with delayed phase imaging to quantify diffuse fibrosis of the myocardium. CT extracellular volume (CT-ECV) measurement correlates well with CMR and histological myocardial fibrosis. Furthermore, CT-ECV predicts outcomes such as death, heart failure and arrhythmia in various disease states. This review summarizes the rationale and methodology behind CT-ECV measurement and provides a detailed summary of the current clinical evidence for the use of CT-ECV.

Citing Articles

Tissue characterisation with cardiac computed tomography: an intriguing possibility becoming reality.

Guglielmo M, Fedele D Int J Cardiovasc Imaging. 2024; 40(11):2233-2235.

PMID: 39497004 DOI: 10.1007/s10554-024-03285-7.

References
1.
Ohta Y, Kitao S, Yunaga H, Fujii S, Mukai N, Yamamoto K . Myocardial Delayed Enhancement CT for the Evaluation of Heart Failure: Comparison to MRI. Radiology. 2018; 288(3):682-691. DOI: 10.1148/radiol.2018172523. View

2.
Gonzalez-Lopez E, Gallego-Delgado M, Guzzo-Merello G, de Haro-Del Moral F, Cobo-Marcos M, Robles C . Wild-type transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction. Eur Heart J. 2015; 36(38):2585-94. DOI: 10.1093/eurheartj/ehv338. View

3.
Hayashi H, Oda S, Emoto T, Kidoh M, Nagayama Y, Nakaura T . Myocardial extracellular volume quantification by cardiac CT in pulmonary hypertension: Comparison with cardiac MRI. Eur J Radiol. 2022; 153:110386. DOI: 10.1016/j.ejrad.2022.110386. View

4.
Jablonowski R, Wilson M, Do L, Hetts S, Saeed M . Multidetector CT measurement of myocardial extracellular volume in acute patchy and contiguous infarction: validation with microscopic measurement. Radiology. 2014; 274(2):370-8. DOI: 10.1148/radiol.14140131. View

5.
Hein S, Arnon E, Kostin S, Schonburg M, Elsasser A, Polyakova V . Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms. Circulation. 2003; 107(7):984-91. DOI: 10.1161/01.cir.0000051865.66123.b7. View